化学样品前处理设备的研制及应用  

Development and application of pretreatment equipment for chemical samples

作　　者：王晓香 时雪钊[2] 陈鹏飞 WANG Xiaoxiang;SHI Xuezhao;CHEN Pengfei(State Key Laboratory of Cryospheric Science,Northwest Institute of Eco-Environment and Resources,Chinese Academy of Sciences,Lanzhou 730000,China;Department of Chemistry,Lanzhou University,Lanzhou 730000,China)

机构地区：[1]冰冻圈科学国家重点实验室,中国科学院西北生态环境资源研究院,兰州730000 [2]兰州大学化学化工学院,兰州730000

出　　处：《分析试验室》2024年第6期828-833,共6页Chinese Journal of Analysis Laboratory

基　　金：中科院仪器功能开发与技术创新项目(Y451H8);国家自然科学基金创新研究群体项目(Y211661)资助。

摘　　要：设计开发了一套多功能样品前处理设备,可在线或离线完成样品处理。该设备以电渗析原理为基础,将膜交换与阀切换技术组合使用,实现了酸碱中和、除盐、过滤、稀释、浓缩、基体消除等功能。通过实验验证了仪器的可靠性和可行性。采用75μm的树脂和1.5 mm管径,得到最佳中和容量;中和能力可通过调节电流大小进行调控。饱和溶液的中和/除盐效率达100%, 2~100倍稀释,连续8次测试的相对标准偏差(RSD)<5%;浓缩连续5次进样的RSD<4.5%。基体消除能力强,甲醇处理后可直接进入分析仪器进行测试。各功能可自由组合,也可连接离子色谱、等离子体质谱等仪器,进行在线样品前处理;特别是设备中和单元,可在线自动再生,弥补了现有技术的不足。该设备可广泛应用于食品、化工、生物、医药、水处理、核电、环境和材料等领域的样品前处理。Based on the principle of electrodialysis,a multi-functional sample pretreatment equipment,which can complete sample processing online or offline,was designed and developed.The equipment combines membrane exchange and valve switching technology to achieve acid-base neutralization,desalination,filtration,dilution,concentration,matrix elimination and other functions.The reliability and feasibility of the instrument were verified through experiments.When the equipment uses 75μm resin and 1.5 mm pipe,the optimal neutralization capacity can be obtained,which can be controlled by tuning the current.The neutralization/desalination efficiency of the saturated solution reached 100%,with the relative standard deviation(RSD)less than 5%for 8 times consecutive dilutions at 2 to 100 times,and the RSD was less than 4.5%for 5 consecutive injection tests for concentration.The matrix elimination ability of this equipment is excellent,the samples can be directly fed into analysis instruments after methanol treatment.Each function can be freely combined or be connected to analytical instruments such as ion chromatography and plasma mass spectrometry for sample pre-treatment.Especially,the neutralization unit of the equipment can automatically regenerate online,which compensates for the shortcomings of existing technology.This equipment can be widely applied in sample pretreatment in food,chemical,biology,medicine,water treatment,nuclear power,environment and materials fields.

关 键 词：前处理 设备研制 电渗析 中和 应用 

分 类 号：TH122[机械工程—机械设计及理论]