Recent advances and innovations in the design and fabrication of wearable flexible biosensors and human health monitoring systems based on conjugated polymers  

作　　者：Vinh Van Tran Viet-Duc Phung Daeho Lee 

机构地区：[1]Department of Mechanical Engineering,Gachon University,Seongnam 13120,Republic of Korea [2]Institute of Fundamental and Applied Sciences,Duy Tan University,Ho Chi Minh City 700000,Vietnam [3]Faculty of Environmental and Chemical Engineering,Duy Tan University,Da Nang 550000,Vietnam

出　　处：《Bio-Design and Manufacturing》2024年第4期476-516,共41页生物设计与制造（英文）

基　　金：supported by the National Research Foundation of Korea(NRF)grant funded by the Korea Government(MSIT)(No.NRF-2021R1A2C2004109);the Korea Institute for Advancement of Technology(KIAT)grant funded by the Korea Government(MOTIE)(No.P0020612,2022 The Competency Development Program for Industry Specialist).

摘　　要：Wearable biosensors have received great interest as patient-friendly diagnostic technologies because of their high flexibility and conformability.The growing research and utilization of novel materials in designing wearable biosensors have accelerated the development of point-of-care sensing platforms and implantable biomedical devices in human health care.Among numerous potential materials,conjugated polymers(CPs)are emerging as ideal choices for constructing high-performance wearable biosensors because of their outstanding conductive and mechanical properties.Recently,CPs have been extensively incorporated into various wearable biosensors to monitor a range of target biomolecules.However,fabricating highly reliable CP-based wearable biosensors for practical applications remains a significant challenge,necessitating novel developmental strategies for enhancing the viability of such biosensors.Accordingly,this review aims to provide consolidated scientific evidence by summarizing and evaluating recent studies focused on designing and fabricating CP-based wearable biosensors,thereby facilitating future research.Emphasizing the superior properties and benefits of CPs,this review aims to clarify their potential applicability within this field.Furthermore,the fundamentals and main components of CP-based wearable biosensors and their sensing mechanisms are discussed in detail.The recent advancements in CP nanostructures and hybridizations for improved sensing performance,along with recent innovations in next-generation wearable biosensors are highlighted.CPbased wearable biosensors have been—and will continue to be—an ideal platform for developing effective and user-friendly diagnostic technologies for human health monitoring.

关 键 词：Conjugated polymers Wearable biosensors E-skin electronics Implantable biosensors Conductive polymer hydrogels 

分 类 号：TP212.3[自动化与计算机技术—检测技术与自动化装置] TH789[自动化与计算机技术—控制科学与工程]