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作 者:张宇 王嵩 段文佳 张蓓 郤庆 李国文 ZHANG Yu;WANG Song;DUAN Wenjia;ZHANG Bei;XI Qing;LI Guowen(Ouyang Road Community Health Service Center of Hongkou District,Shanghai,China 200081;Shanghai TCM-Integrated Hospital Affiliated to Shanghai University of TCM,Shanghai,China 200082;Huamu Community Health Service Center of Pudong New Area,Shanghai,China 201204)
机构地区:[1]上海市虹口区欧阳路街道社区卫生服务中心,上海200081 [2]上海中医药大学附属上海市中西医结合医院,上海200082 [3]上海市浦东新区花木社区卫生服务中心,上海201204
出 处:《中国药业》2024年第15期127-128,I0001-I0004,共6页China Pharmaceuticals
基 金:国家中医药管理局全国中药特色技术传承人才培训项目[国中医药人教函[2023]96号];上海市“科技创新行动计划”生物医药科技支撑项目[21S21901000];上海市“医苑新星”青年医学人才培养资助计划[沪卫计人事[2019]72号]。
摘 要:目的 总结中药外用制剂的研究现状。方法 检索中国知网(CNKI)、维普(VIP)、万方(WanFang)、PubMed等数据库中的中药外用制剂相关文献,总结其临床应用现状,并提出发展建议。结果 中药外用制剂是以中医药理论为基础,辅以适当的剂型,通过皮肤、黏膜、腔道等途径给药,局部作用于病灶部位,减少胃肠道刺激,避免首过效应。通过现用制剂的二次开发,建立含毒性中药外用制剂的标准规范,扩展中药外用制剂功效,推动经典名方的研究,中药外用制剂的研究现状可进一步得到改善。结论 中药外用制剂是我国特有的中医外治法用药的重要组成部分,应用历史悠久,与口服制剂共同发挥着不可替代的作用。Objective To summarize the research status of topical preparations of traditional Chinese medicine (TCM).Methods Literature related to TCM topical preparations in databases such as CNKI,VIP,WanFang,and PubMed were searched to summarize the clinical application status,and development suggestions were put forward.Results TCM topical preparations are based on the theory of TCM,supplemented by appropriate dosage forms and administered through the skin,mucous membrane or cavity.TCM topical preparations can act on the site of the lesion locally,reduce gastrointestinal irritation,and avoid first-pass effects.The research status of TCM topical preparations can be further improved through the secondary development of current preparations,the establishment of standard specifications for toxic TCM topical preparations,the expansion of the efficacy of TCM topical preparations,and the promotion of research on classic formulas.Conclusion TCM topical preparation is an important part of TCM unique external therapy method in China,with a long history of application,and plays an irreplaceable role together with oral preparations.
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