老年高尿酸血症人群中医证型与检验指标的关系  

Relationship between Traditional Chinese Medicine Syndrome Types and Laboratory Indicators in Elderly Hyperuricemia Population

作　　者：赵阳阳 刘琴 吴晓燕 ZHAO Yangyang;LIU Qin;WU Xiaoyan(Department of Laboratory,Qingpu District Traditional Chinese Medicine Hospital,Shanghai 201700,China;Department of Nephrology,Qingpu District Traditional Chinese Medicine Hospital,Shanghai 201700,China)

机构地区：[1]青浦区中医医院检验科,上海201700 [2]青浦区中医医院肾内科,上海201700

出　　处：《临床研究》2024年第8期9-12,共4页Clinical Research

基　　金：老年人群高尿酸血症中医药健康服务体系的构建(2022KJCX002)。

摘　　要：目的探讨老年高尿酸血症(HUA)人群中医证属肾虚痰瘀型和脾虚湿热型与检验指标[尿酸(UA)、血糖(GLU)、肾小球滤过率(eGFR)、血尿素氮(BUN)]的关系,为患有老年高尿酸血症的个体进行中医辨证分型的辅助诊断,以提供客观的临床指导和依据。方法选取上海市青浦区中医医院2023年6月至2023年9月60岁及以上老年体检人群高尿酸血症者189例(肾虚痰瘀型97例,脾虚湿热型92例)和同期老年健康体检者(94例)作为对照组。对于高尿酸血症患者和健康体检者,进行了比较,分析了两种不同中医证型下尿酸、血糖、肾小球滤过率和尿素氮等数据指标。结果肾虚痰瘀型和脾虚湿热型高尿酸血症人群UA水平差异无统计学意义(P>0.05);eGFR:肾虚痰瘀型<脾虚湿热型<对照组,差异均有统计学意义(P<0.05);三组之间的GLU和BUN水平差异无统计学意义(P>0.05)。结论肾虚痰瘀型高尿酸血症患者eGFR水平明显低于脾虚湿热型高尿酸血症患者,因此eGFR可作为高尿酸血症中医辨证分型的参考依据。Objective To explore the relationship between the laboratory indicators[uric acid(UA),blood glucose(GLU),glomerular filtration rate(eGFR),blood urea nitrogen(BUN)]and the syndrome types of kidney deficiency and phlegm stasis,and spleen deficiency and damp heat in elderly hyperuricemia(HUA)population,to provide objective clinical guidance and basis for the auxiliary diagnosis of traditional Chinese medicine syndrome differentiation in individuals with elderly hyperuricemia.Methods 189 cases of elderly hyperuricemia(97 cases of kidney deficiency and phlegm stasis type,92 cases of spleen deficiency and damp heat type)and 94 cases of elderly healthy physical examination in the same period were selected from the physical examination population aged 60 and above in Qingpu District Traditional Chinese Medicine Hospital in Shanghai from June 2023 to September 2023 as the control group.For patients with hyperuricemia and healthy physical examination,a comparison was made,and the data indicators such as uric acid,blood glucose,glomerular filtration rate,and urea nitrogen under two different traditional Chinese medicine syndrome types were analyzed.Results There was no significant difference in UA level between kidney deficiency and phlegm stasis type and spleen deficiency and damp heat type hyperuricemia population(P>0.05);eGFR:kidney deficiency and phlegm stasis type<spleen deficiency and damp heat type<healthy group,the difference was statistically significant(P<0.05);there was no significant difference in GLU and BUN levels among the three groups(P>0.05).Conclusion The eGFR level of patients with kidney deficiency and phlegm stasis type hyperuricemia is significantly lower than that of patients with spleen deficiency and damp heat type hyperuricemia,therefore,eGFR can be used as a reference for the syndrome differentiation of hyperuricemia in traditional Chinese medicine.

关 键 词：高尿酸血症 中医辩证分型 肾小球滤过率 

分 类 号：R692.6[医药卫生—泌尿科学]