消炎利胆汤治疗肝胆湿热型重症急性胰腺炎的临床效果  

Clinical Effect of Xiaoyan Lidan Decoction in the Treatment of Severe Acute Pancreatitis of Hepatobiliary Damp-Heat Type

作　　者：杨成祥 张刚 董士海 滕飞 YANG Chengxiang;ZHANG Gang;DONG Shihai;TENG Fei(Department of Gastroenterology,Xinyang People’s Hospital,Xinyang Henan 464200,China)

机构地区：[1]信阳市人民医院消化内科,河南信阳464200

出　　处：《临床研究》2024年第8期117-120,共4页Clinical Research

摘　　要：目的探讨肝胆湿热型重症急性胰腺炎(SAP)患者采用消炎利胆汤治疗的临床效果。方法选取2020年8月至2023年8月在信阳市人民医院接受治疗的60例肝胆湿热型SAP患者,以随机数字表法分为对照组(n=30)与研究组(n=30),对照组采用乌司他丁治疗,研究组采用消炎利胆汤联合乌司他丁治疗,对两组临床疗效、症状改善时间、中医证候积分、胃肠道功能[胃肠道症状评定量表(GSRS)]、不良反应进行比较。结果研究组治疗有效率(93.33%)高于对照组(70.00%),差异具有统计学意义(P<0.05);研究组腹痛消失、腹胀消失、肠鸣音恢复、血清淀粉酶恢复时间均短于对照组,差异均有统计学意义(P<0.05);两组治疗后各项中医证候积分均下降,且研究组各项中医证候积分均低于对照组,差异均有统计学意义(P<0.05);两组治疗后GSRS评分下降,且研究组GSRS评分低于对照组,差异均有统计学意义(P<0.05);研究组不良反应发生率(10.00%)低于对照组(36.67%),差异具有统计学意义(P<0.05)。结论消炎利胆汤应用于肝胆湿热型SAP患者治疗中,能够提高临床疗效,缩短临床症状改善时间,降低中医证候积分,改善胃肠道功能,减少不良反应。Objective To explore the clinical effect of Xiaoyan Lidan Decoction in the treatment of severe acute pancreatitis(SAP)patients of hepatobiliary damp-heat type.Methods 60 patients with hepatobiliary damp-heat type SAP treated in Xinyang People’s Hospital from August 2020 to August 2023 were selected and divided into a control group(n=30)and a research group(n=30)by random number table method.The control group was treated with ursodeoxycholic acid,and the research group was treated with Xiaoyan Lidan Decoction combined with ursodeoxycholic acid.The clinical efficacy,symptom improvement time,traditional Chinese medicine syndrome score,gastrointestinal function[Gastrointestinal Symptom Rating Scale(GSRS)],and adverse reactions of the two groups were compared.Results The effective rate of treatment in the research group(93.33%)was higher than that in the control group(70.00%),with a statistically significant difference(P<0.05).The disappearance time of abdominal pain,bloating,recovery of bowel sounds,and recovery time of serum amylase in the research group were all shorter than those in the control group,with statistically significant differences(P<0.05).After treatment,the traditional Chinese medicine syndrome scores of both groups decreased,and the scores of the research group were lower than those of the control group,with statistically significant differences(P<0.05).After treatment,the GSRS scores of both groups decreased,and the GSRS score of the research group was lower than that of the control group,with statistically significant differences(P<0.05).The incidence of adverse reactions in the research group(10.00%)was lower than that in the control group(36.67%),with a statistically significant difference(P<0.05).Conclusion The application of Xiaoyan Lidan improvement time,reduce the traditional Chinese medicine syndrome score,improve gastrointestinal function,and reduce adverse reactions.

关 键 词：消炎利胆汤 肝胆湿热型 重症急性胰腺炎 临床效果 

分 类 号：R657.51[医药卫生—外科学]