天山雪莲的化学成分及主要药理作用研究进展  

Research Progress on Chemical Components and Main Pharma-cological Effects of Saussurea Involucrate Kar.et Kir

作　　者：迟平原 阿依先木古力·依明 金滢 刘明远 CHI Pingyuan;AYIXIANMUGULI Yiming;JIN Ying;LIU Mingyuan(College of Pharmacy,Jiamusi University,Jiamusi,Heilongjiang 154007,China;Department of Traditional Chinese Medicine,the First Hospital of the Xinjiang Production and Construction Corps,Akesu Prefecture,Xinjiang Uygur Autonomous Region 843000,China;Institute of Cardiovascular Disease,the First Affiliated Hospital of Xiamen University,Xiamen,Fujian 361003,China)

机构地区：[1]佳木斯大学药学院,黑龙江佳木斯154007 [2]新疆生产建设兵团第一师医院中医科,新疆维吾尔自治区阿克苏地区843000 [3]厦门大学附属第一医院心血管病研究所,福建厦门361003

出　　处：《临床误诊误治》2024年第12期88-100,共13页Clinical Misdiagnosis & Mistherapy

基　　金：国家自然科学基金委员会资助项目计划书(U1903119)。

摘　　要：天山雪莲化学成分包括黄酮、香豆素、倍半萜内酯、苯丙素、有机酸、甾体、鞘脂、挥发油等多种类型。天山雪莲丰富的化学成分也决定了其广泛的药理作用,如抗炎镇痛、抗肿瘤、抗氧化、免疫调节、降血脂等。本文通过查阅大量国内外文献资料,总结和阐述了天山雪莲国内外的研究状况、化学成分和药理作用,以期为全面了解并合理开发天山雪莲资源提供参考。The chemical components of Saussureainvolucrate Kar.et Kir include flavonoids,coumarins,sesquiter-pene lactones,phenylpropanoids,organic acids,steroids,sphingolipids,and volatile oils.The rich chemical components of SaussureainvolucrateKar.et Kir also determine its extensive pharmacological effects,such as anti-inflammatory,analgesic,anti-tumor,anti-oxidant effect,immune regulation,and lowering blood lipids.This article summarizes and expounds the research status,chemical components and pharmacological effects of SaussureainvolucrateKar.et Kir at home and abroad by reviewing a large number of domestic and foreign literature,in order to provide a reference for a comprehensive understanding and ratio-nal development of SaussureainvolucrateKar.et Kir resources.

关 键 词：天山雪莲 化学成分 黄酮类 香豆素类 有机酸类 鞘脂类 药理活性 综述 

分 类 号：R282.7[医药卫生—中药学]