菌酶协同发酵复方中草药对断奶仔猪生长性能及血清免疫、抗氧化和生长相关激素指标的影响  

Effects of Compound Chinese Herbal Medicine Fermented with Bacteria and Enzymes on Growth Performance and serum Immune,Antioxidant and Growth-Related Hormone Indices of Weaned Piglets

作　　者：刘显军[1] 苏晴 马旭东 陈静[1] 刘明亮 李玟 李海东 王欣宇[1] 郭家豪 LIU Xianjun;SU Qing;MA Xudong;CHEN Jing;LIU Mingliang;LI Wen;LI Haidong;WANG Xinyu;GUO Jiahao(College of Animal Science and Medicine,Shenyang Agricultural University,Shenyang 110866,China)

机构地区：[1]沈阳农业大学动物科学与医学学院,沈阳110866

出　　处：《动物营养学报》2024年第7期4233-4242,共10页CHINESE JOURNAL OF ANIMAL NUTRITION

基　　金：辽宁省科技攻关专项(2022JH1/10400014);辽宁省种质创新藏粮于技专项(2023JH1/10200006);沈阳市科技攻关专项(21-110-3-07)。

摘　　要：本试验旨在研究饲粮中添加菌酶协同发酵复方中草药对断奶仔猪生长性能及血清免疫、抗氧化和生长相关激素指标的影响,为复方中草药在断奶仔猪生产上的应用提供理论依据。试验采用单因素随机化设计,选用健康、体重相近的(28±2)日龄断奶仔猪160头,随机分为4个组,每组5个重复,每个重复8头猪(公母各占1/2)。对照组饲喂基础饲粮,试验组分别在基础饲粮中添加0.5%、1.0%、2.0%的菌酶协同发酵复方中草药。试验期为28 d。结果表明:1)与对照组相比,0.5%、1.0%和2.0%菌酶协同发酵复方中草药组的平均日增重显著升高(P<0.05),平均日采食量和料重比显著降低(P<0.05)。2)与对照组相比,0.5%、1.0%和2.0%菌酶协同发酵复方中草药组的血清免疫球蛋白A(IgA)和免疫球蛋白M(IgM)含量显著升高(P<0.05),血清白细胞介素-6(IL-6)含量显著降低(P<0.05);1.0%菌酶协同发酵复方中草药组的血清免疫球蛋白G(IgG)、白蛋白(ALB)和总蛋白(TP)含量显著升高(P<0.05),血清白细胞介素-1(IL-1)含量显著降低(P<0.05)。3)与对照组相比,1.0%和2.0%菌酶协同发酵复方中草药组的血清总抗氧化能力(T-AOC)、超氧化物歧化酶(SOD)活性和还原型谷胱甘肽(GSH)含量显著升高(P<0.05),1.0%菌酶协同发酵复方中草药组的血清丙二醛(MDA)含量显著降低(P<0.05)。4)与对照组相比,0.5%、1.0%和2.0%菌酶协同发酵复方中草药组的血清生长激素(GH)和胃泌素(GAS)含量显著升高(P<0.05),血清皮质醇(COR)含量显著降低(P<0.05);1.0%菌酶协同发酵复方中草药组的血清胰岛素生长因子-1(IGF-1)、三碘甲状腺原氨酸(T 3)和四碘甲状腺原氨酸(T 4)含量显著升高(P<0.05)。由此可见,饲粮中添加菌酶协同发酵复方中草药能够提高断奶仔猪生长性能,增强机体免疫功能和抗氧化能力,提高血清生长相关激素含量。本试验条件下,饲粮中菌酶协同发酵复方中草药适宜添加水平为1.0%。The purpose of this experiment was to study the effects of dietary compound Chinese herbal medicine fermented with bacteria and enzymes on growth performance and serum immune,antioxidant and growth-related hormone indices of weaned piglets,to provide a theoretical basis for the application of compound Chinese herbal medicine in the production of weaned piglets.In this study,a single variate randomization design was adopted,and a total of 160 healthily weaned piglets at(28±2)days of age with similar body weight were randomly divided into 4 groups with 5 replicates per group and 8 pigs per replicate(half male and half female).Pigs in the control group were fed a basal diet,and others in experimental groups were fed the basal diets supplemented with 0.5%,1.0% and 2.0% compound Chinese herbal medicine fermented with bacteria and enzymes,respectively.The experiment lasted for 28 days.The results showed as follows:1)compared with the control group,the average daily gain of 0.5%,1.0% and 2.0% compound Chinese herbal medicine fermented with bacteria and enzymes groups was significantly increased(P<0.05),and the average daily feed intake and feed to gain ratio were significantly decreased(P<0.05).2)Compared with the control group,the contents of immunoglobulin A(IgA)and immunoglobulin M(IgM)in serum of 0.5%,1.0% and 2.0% compound Chinese herbal medicine fermented with bacteria and enzymes groups was significantly increased(P<0.05),and the serum interleukin-6(IL-6)content was significantly decreased(P<0.05);the contents of immunoglobulin G(IgG),albumin(ALB)and total protein(TP)of 1.0% compound Chinese herbal medicine fermented with bacteria and enzymes group was significantly increased(P<0.05),and the serum interleukin-1(IL-1)content was significantly decreased(P<0.05).3)Compared with the control group,the serum total antioxidant capacity(T-AOC),superoxide dismutase(SOD)activity and reduced glutathione(GSH)content of 1.0% and 2.0% compound Chinese herbal medicine fermented with bacteria and enzymes groups was significantl

关 键 词：菌酶协同发酵 复方中草药 断奶仔猪 生长性能 免疫 抗氧化 激素 

分 类 号：S828[农业科学—畜牧学]