双侧乳晕入路腔镜甲状腺切除手术对良性甲状腺疾病患者的影响  

Effect of Bilateral Areola Approach Endoscopic Thyroidectomy on Patients with Benign Thyroid Disease

作　　者：吴剑纯 彭紫荆 WU Jianchun;PENG Zijing(The Third Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine,Guangzhou 510000,China;不详)

机构地区：[1]广州中医药大学第三附属医院,广东广州510000

出　　处：《中外医学研究》2024年第20期155-158,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:研究双侧乳晕入路腔镜甲状腺切除手术(ET)对良性甲状腺疾病患者的影响。方法:选取2020年6月—2023年5月广州中医药大学第三附属医院收治的60例良性甲状腺疾病患者。根据抽签法将其分为干预组和对照组,各30例。对照组给予传统甲状腺切除手术,干预组给予双侧乳晕入路ET治疗。比较两组围手术期指标,术后1个月、3个月美观满意,术后6 h、12 h、24 h疼痛情况,术前及术后炎症因子,并发症。结果:干预组手术时间、术后引流时间、住院时间均短于对照组,术中出血量及术后引流量均少于对照组,差异有统计学意义(P<0.05)。术后1个月、3个月,干预组数字评分系统(NSS)评分高于对照组;术后6 h、12 h、24 h,干预组视觉模拟评分法(VAS)评分低于对照组,差异有统计学意义(P<0.05)。术后2 d,两组肿瘤坏死因子-α(TNF-α)与白细胞介素-6(IL-6)水平均升高,干预组TNF-α、IL-6水平均低于对照组,差异有统计学意义(P<0.05)。干预组术后并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论:双侧乳晕入路ET应用于良性甲状腺疾病治疗中的效果显著,能优化围手术期指标,外周血TNF-α及IL-6水平低,获得更佳的美容效果。Objective:To investigate the effect of bilateral areola approach endoscopic thyroidectomy(ET)on patients with benign thyroid disease.Method:Sixty patients with benign thyroid disease admitted to the Third Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine from June 2020 to May 2023 were selected.They were divided into intervention group and control group according to the lottery method,with 30 cases in each group.The control group was treated with traditional thyroidectomy and the intervention group was treated with bilateral areola approach ET.The perioperative indicators,satisfied with aesthetics at 1 month and 3 months after surgery,pain condition at 6 h,12 h,and 24 h after surgery,preoperative and postoperative inflammatory factors,and complications were compared between the two groups.Result:The surgery time,postoperative drainage time and hospital stay in the intervention group were shorter than those in the control group,and the intraoperative blood loss volume and postoperative drainage volume were less than those in the control group,the differences were statistically significant(P<0.05).At 1 month and 3 months after surgery,the numeric score system(NSS)scores in the intervention group were higher than those in the control group.At 6 h,12 h,24 h after surgery,the visual analogue scale(VAS)scores of the intervention group were lower than those of the control group,and the differences were statistically significant(P<0.05).After 2 d of surgery,the levels of tumor necrosis factor-α(TNF-α)and interleukin-6(IL-6)were increased in both groups,and the levels of TNF-αand IL-6 in the intervention group were lower than those in the control group,and the differences were statistically significant(P<0.05).The incidence of postoperative complications in the intervention group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion:Bilateral areola approach ET has a remarkable effect in the treatment of benign thyroid diseases,which can optim

关 键 词：双侧乳晕入路腔镜甲状腺切除手术 良性甲状腺疾病 围手术期指标 肿瘤坏死因子-Α 白细胞介素-6 

分 类 号：R653[医药卫生—外科学]