维生素AD联合锌剂治疗呼吸道合胞病毒肺炎的效果  

Effect of Vitamin AD Combined with Zinc Agent in the Treatment of Respiratory Syncytial Virus Pneumonia

作　　者：廖丽娟 王会丰 陈志玮 LIAO Lijuan;WANG Huifeng;CHEN Zhiwei(Shenzhen Longhua District Maternal and Child Health Hospital,Shenzhen 518000,China;不详)

机构地区：[1]深圳市龙华区妇幼保健院,广东深圳518000

出　　处：《中外医学研究》2024年第19期1-4,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

基　　金：深圳市龙华区医疗卫生机构区级科研项目(2022154)。

摘　　要：目的:研究维生素AD联合锌剂治疗呼吸道合胞病毒肺炎(RSVP)的效果。方法:选取2022年7月—2023年10月深圳市龙华区妇幼保健院收治的200例RSVP患儿作为研究对象,随机分为A组、B组、C组、D组,各50例。A组给予常规治疗;B组在常规治疗基础上单独给予维生素AD治疗;C组在常规治疗基础上单独给予锌剂治疗;D组在常规治疗用药基础上,予以维生素AD及锌剂的联合治疗。比较四组临床疗效、症状改善时间、免疫功能指标及不良反应发生情况。结果:D组总有效率高于A组、B组及C组,差异有统计学意义(P<0.05)。D组退热、喘息改善时间均早于A组,咳嗽、气促及肺部哮鸣音改善时间均早于A组、B组、C组,且C组咳嗽改善时间早于A组、B组,B组、C组气促及肺部哮鸣音改善时间均早于A组,差异有统计学意义(P<0.05)。治疗后,四组免疫球蛋白E(IgE)、免疫球蛋白A(IgA)、免疫球蛋白G(IgG)均高于治疗前,且D组均高于A组、B组、C组,B组、C组均高于A组,差异有统计学意义(P<0.05)。四组药物不良反应总发生率比较,差异无统计学意义(P>0.05)。结论:维生素AD联合锌剂治疗RSVP患儿的效果较好,能够有效改善其临床症状及机体的免疫功能,且安全性较高。Objective:To study the effect of vitamin AD combined with Zinc agent on respiratory syncytial virus pneumonia(RSVP).Method:A total of 200 children with RSVP admitted to Shenzhen Longhua District Maternal and Child Health Hospital from July 2022 to October 2023 were selected as the study objects and randomly divided into group A,group B,group C and group D,with 50 cases in each group.Group A received conventional treatment;group B was given vitamin AD alone on the basis of conventional treatment;group C was separately treated with Zinc agent on the basis of conventional treatment;group D was treated with vitamin AD and Zinc agent on the basis of the conventional treatment.The clinical efficacy,symptom improvement time,immune function indexes and adverse reactions of the four groups were compared.Result:The total effective rate of group D was higher than that of group A,group B and group C,and the difference was statistically significant(P<0.05).The improvement time of fever and wheezing in group D were earlier than those in group A,the improvement time of cough,shortness of breath and pulmonary wheezing sound were earlier than those in group A,group B and group C,and the improvement time of cough in group C was earlier than that in group A and group B,and the improvement time of shortness of breath and pulmonary wheezing sound in group B and group C were earlier than those in group A,the differences were statistically significant(P<0.05).After treatment,immunoglobulin E(IgE),immunoglobulin A(IgA),immunoglobulin G(IgG)in the four groups were higher than those before treatment,and those in group D were higher than those in group A,group B and group C,and those in group B and group C were higher than those in group A,the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of adverse drug reactions among the four groups(P>0.05).Conclusion:Vitamin AD combined with Zinc agent is effective in the treatment of RSVP children,which can effectively improve their clini

关 键 词：维生素AD 锌剂 呼吸道合胞病毒 肺炎 疗效 

分 类 号：R725.6[医药卫生—儿科]