不孕年限对30岁以下育龄女性FET结局的影响  

Influence of years of infertility on FET outcomes in women of reproductive age under 30 years of age

作　　者：杜娟 张艳茹 刘兰香 DU Juan;ZHANG Yanru;LIU Lanxiang(Department of Reproductive Medicine,Wuxi People’s Hospital,Wuxi 214023,Jiangsu,China;Department of Reproductive Center,the 904th Hospital of Joint Logistic Support Force of PLA,Wuxi 214000,Jiangsu,China)

机构地区：[1]无锡市人民医院生殖医学科,江苏无锡214023 [2]中国人民解放军联勤保障部队第九〇四医院生殖中心,江苏无锡214007

出　　处：《中国现代医生》2024年第20期94-98,共5页China Modern Doctor

摘　　要：目的探讨不孕年限对30岁以下育龄女性冻融胚胎移植(frozen-thawed embryo transfer,FET)结局的影响。方法回顾性分析生殖中心540例FET周期,根据临床妊娠与否,分临床妊娠组和非临床妊娠组;再按患者不孕年限分为四组:A组(1~2年)、B组(3~4年)、C组(5~6年)和D组(7~8年),分析比较各组的基础资料、临床妊娠结局的差异。结果各组间基础资料比较,年龄差异有统计学意义(P<0.05),其余均差异无统计学意义;C组的临床妊娠率(33.93%)和胚胎着床率(25%)均最低,但只有临床妊娠率的差异有统计学对意义(P<0.05);四组间的早期流产率差异无统计学意义(P>0.05)。结论不孕年限对30岁以下育龄女性FET的临床妊娠率有影响,但并不是随着不孕年限时间越长影响越显著。Objective To investigate the influence of infertility duration on the outcomes of frozen-thawed embryo transfer(FET)in women under 30 years old.Methods A retrospective analysis was conducted on 540 FET cycles at reproductive center.The cycles were categorized into clinical pregnancy and non-clinical pregnancy groups based on the occurrence of clinical pregnancy.Furthermore,patients were stratified into four groups based on infertility duration:Group A(1-2 years),Group B(3-4 years),Group C(5-6 years),and Group D(7-8 years).Differences in baseline characteristics and clinical pregnancy outcomes among the groups were analyzed.Results Baseline characteristics showed statistical significance only in age differences among the groups(P<0.05),with no other significant differences.The clinical pregnancy rate(33.93%)and embryo implantation rate(25%)in group C were the lowest,but only the difference in clinical pregnancy rate was statistically significant(P<0.05).Early miscarriage rates did not show significant differences among the four groups.Conclusion Infertility duration has a discernible impact significant impact on clinical pregnancy rate of FET in women under 30 years old.However,the effect does not linearly increase with longer infertility duration.

关 键 词：冻融胚胎移植 临床妊娠率 着床率 早期流产率 

分 类 号：R692[医药卫生—泌尿科学]