尖尾芋炮制前后质量比较研究  

Comparative Study on Quality of Alocasia cucullata before and after Processing

作　　者：莫单丹[1] 张颖婷 殴春丽 龚小妹[1] 周小雷[1] 王硕[1] 唐炳兰[1] MO Dandan;ZHANG Yingting;OU Chunli;GONG Xiaomei;ZHOU Xiaolei;WAND Shuo;TANG Binglan(Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement,National Center for TCM Inheritance and Innovation,Guangxi Botanical Gardenof Medicinal Plants,Nanning 530023,China;Guangxi Zhuang Autonomous Region Food and Drug Inspection Institute,Nanning 530022,China)

机构地区：[1]广西壮族自治区药用植物园,国家中医药传承创新中心,广西药用资源保护与遗传改良重点实验室,广西南宁530023 [2]广西壮族自治区食品药品检验所,广西南宁530022

出　　处：《中国民族民间医药》2024年第14期22-27,共6页Chinese Journal of Ethnomedicine and Ethnopharmacy

基　　金：广西壮族自治区药品监督管理局药品安全科研项目:瑶药材老虎芋炮制品质量标准研究;广西壮族自治区中医药管理局科研课题(GXZYA20220004)。

摘　　要：目的:研究尖尾芋炮制前后(尖尾芋生品和米炒尖尾芋)显微结构、薄层色谱、指纹图谱的变化。方法:观察尖尾芋生品及其炮制品药材粉末的显微鉴别特征,采用TLC对尖尾芋生品及其炮制品进行鉴别,采用HPLC法建立尖尾芋生品及其炮制品指纹图谱。结果:尖尾芋经米炒炮制后草酸钙针晶形态、TLC及HPLC指纹图谱均发生明显改变,指纹图谱相似度均大于0.9,归纳出尖尾芋药材10个共有峰,米炒尖尾芋8个共有峰。结论:比较了尖尾芋药材与其制品之间显微、TLC及指纹图谱的差异,为尖尾芋及米炒尖尾宇质量控制提供方法依据。Objective To study the changes of microstructures,thin layer chromatography(TLC)and fingerprint spectra of Alocasia cucullata before and after processing.Methods To observe the microscopic identification characteristics of taro and its processed products,the raw products and its products were identified by TLC,and the fingerprints of the raw products and its products were established by HPLC.Results After processing,the morphology of calcium oxalate needle crystals,TLC and HPLC fingerprints were significantly changed.The similar degree of 10 batch samplesbuiding sharing mode of crude drnug and processed product was above 0.9,10 common peaks in chromatograms were separated from 10 batches of Alocasia cucullata samples and 8common peaks in chromalograms were separated from 10 batches of the processed.Conclusion In this study,the differences of microstructure,TLC and fingerprint before and after processing were compared,which provided the method basis for quality control of Alocasia cucullata and Alocasia cucullata cooked with rice.

关 键 词：尖尾芋 炮制品 高效液相色谱 指纹图谱 质量标准 

分 类 号：R927.1[医药卫生—药学]