卤代苯醌类消毒副产物的毒理学研究进展  

Research progress on toxicology of haloquinoid disinfection byproducts

作　　者：王芳[1] 赖玮毅[2] 汪海林 WANG Fang;LAI Weiyi;WANG Hailin(Hubei Key Laboratory of Environmental and Health Effects of Persistent Toxic Substances,School of Environment and Health Jianghan University,Wuhan,430056,China;Research Center for Eco-Environmental Sciences,Chinese Academy of Sciences,Beijing,100085,China)

机构地区：[1]江汉大学持久性有毒污染物环境与健康危害湖北省重点实验室,环境与健康学院,武汉430056 [2]中国科学院生态环境研究中心,环境化学与生态毒理学国家重点实验室,北京100085

出　　处：《环境化学》2024年第7期2206-2213,共8页Environmental Chemistry

基　　金：国家自然科学基金-重点项目(22234008);国家自然科学基金-国家重大科研仪器研制项目(21927807);国家自然科学基金-创新研究群体项目(22021003);国家自然科学基金-面上项目(22274166)资助.

摘　　要：卤代苯醌(halobenzoquinones,HBQs)是近年来在水体中发现的一类具有潜在毒理学效应且未受管控的新型消毒副产物(disinfection by-products,DBPs).本文综述了HBQs的化学特征与生成机制、环境中的分布情况,并对其引起的细胞毒性、氧化应激毒性、遗传毒性、生物毒性进行了概述.这些内容旨在为深入探讨HBQs的毒理学机制和全面评估其暴露所可能导致的健康风险及癌症风险提供科学依据.Halobenzoquinones(HBQs)are newly identified,unregulated disinfection by-products(DBPs)with potential toxicity,recently found in various water bodies.This article reviews the chemical properties,and formation mechanisms of HBQs,as well as their environmental distribution.It provides an extensive overview of the toxicological impacts of HBQs exposure,including cytoxicity,oxidative stress toxicity,genetic toxicity,and other biological effects.The goal is to offer a scientific basis for further investigation into the toxicological mechanisms of HBQs and to enhance understanding of the potential health risks associated with HBQs exposure.

关 键 词：卤代苯醌 消毒副产物 环境暴露 毒性评估 

分 类 号：X-1[环境科学与工程] O6[理学—化学]