光子治疗仪联合rh-aFGF治疗小面积深Ⅱ度烧伤创面疗效观察  

Efficacy of Photon Therapeutic Instrument Combined with rh-aFGF in the Treatment of Small-area Deep Partial-thickness Burn

作　　者：王庆 张大维[1] 徐振雷 WANG Qing;ZHANG Dawei;XU Zhenlei(Department of Burn and Plastic Surgery,Huai'an First Hospital Affiliated to Nanjing Medical University,Huai'an 223300,Jiangsu,China)

机构地区：[1]南京医科大学附属淮安第一医院烧伤整形科,江苏淮安223300

出　　处：《中国美容医学》2024年第8期49-52,共4页Chinese Journal of Aesthetic Medicine

摘　　要：目的:探讨光子治疗仪联合重组人酸性成纤维细胞生长因子(Recombinant human acidic fibroblast growth factor,rh-aFGF)对小面积深Ⅱ度烧伤患者创面愈合、疼痛程度的影响。方法:选取2020年6月-2022年11月笔者医院收治的80例小面积深Ⅱ度烧伤患者,采用随机数字表法分为rh-aFGF组(n=40)和联合组(n=40)。rh-aFGF组给予rh-aFGF治疗,联合组给予光子治疗仪联合rh-aFGF治疗,比较两组治疗后10、15、19 d时的创面愈合率、创面肉芽生长评分及完全愈合时间;比较两组治疗后1、7、14 d时的创面疼痛数字量表(Numerical rating scale,NRS)评分;比较两组治疗后6个月时的温哥华瘢痕量表(Vancouver scar scale,VSS)评分。结果:联合组治疗后10、15、19 d创面愈合率、创面肉芽生长评分均高于rh-aFGF组,创面完全愈合时间短于rh-aFGF组(P<0.05)。两组治疗后1、7、14 d创面NRS评分均较治疗前降低,且联合组低于rh-aFGF组(P<0.05)。联合组治疗后6个月VSS评分低于rh-aFGF组(P<0.05)。结论:光子治疗仪联合rh-aFGF治疗小面积深Ⅱ度烧伤,可促进肉芽组织生长,加速创面愈合,减轻疼痛,减少瘢痕形成。Objective To investigate the effect of photon therapeutic instrument combined with recombinant human acidic fibroblast growth factor(rh-aFGF)on wound healing and pain degree in patients with small-area deep partial-thickness burn.Methods 80 patients with small-area deep partial-thickness burn admitted to the author's hospital from June,2020 to November,2022 were divided into rh-aFGF group(n=40)and combined group(n=40)by random number table method.rh-aFGF group was treated with rh-aFGF,and combined group was treated with photon therapeutic apparatus combined with rh-aFGF,the wound healing rate and wound granulation growth score at 10 d,15 d,and 19 d after treatment,and the complete healing time were compared between the two groups.The scoreof numerical rating scale(NRS)was compared between the two groups at 1 d,7 d,and 14 d after treatment.The score of vancouver scar scale(VSS)was compared between the two groups at 6 months after treatment.Results The wound healing rate and wound granulation growth score of combined group were higher than those of rh-aFGF group on 10 d,15 d,and 19 d after treatment,and the complete wound healing time was shorter than that rh-aFGF group(P<0.05).The NRS scores of wounds at 1,7,and 14 days after treatment in the two groups were lower than those before treatment,and those in combined group were lower than those in rhaFGF group(P<0.05).The VSS score of combined group was lower than that of rh-aFGF group at 6 months after treatment(P<0.05).Conclusion The combination of photon therapy instrument and rh-aFGF in the treatment of small area deep seconddegree burn can promote the growth of granulation tissue,accelerate wound healing,reduce pain and reduce scar formation.

关 键 词：深Ⅱ度烧伤 小面积 光子治疗仪 重组人酸性成纤维细胞生长因子 

分 类 号：R644[医药卫生—外科学]