带状疱疹后遗皮肤瘢痕发生情况及危险因素分析  

Analysis of Skin Scar after Herpes Zoster and Its Risk Factors

作　　者：高慧[1] 刘秀燕[1] GAO Hui;LIU Xiuyan(Department of Dermatology,Linfen City People's Hospital,Linfen 041000,Shanxi,China)

机构地区：[1]临汾市人民医院皮肤科,山西临汾041000

出　　处：《中国美容医学》2024年第8期96-98,共3页Chinese Journal of Aesthetic Medicine

摘　　要：目的:分析带状疱疹患者后遗皮肤瘢痕的发生情况及相关影响因素。方法:选取2021年4月-2022年10月至笔者医院接受治疗的185例带状疱疹患者作为研究对象,收集患者性别、年龄、既往病史、严重程度、发病部位等资料,在水疱消退后连续随访6个月,根据皮肤瘢痕的发生情况将其分为瘢痕组和正常组,采用多因素Logistics分析其皮肤瘢痕发生的相关危险因素。结果:最终46例患者出现皮肤瘢痕,139例患者未出现皮肤瘢痕,带状疱疹患者后遗皮肤瘢痕的发生率为24.86%;瘢痕组的年龄、皮损面积均高于正常组,血清IgA、IgG、IgM水平均低于正常组,带状疱疹发生在颜面部的比例、剥除痂皮的比例以及并发糖尿病的比例均高于正常组(P<0.05);多因素Logistics回归分析显示,年龄(OR=2.095,P=0.045)、糖尿病(OR=3.442,P=0.046)、皮损范围(OR=1.467,P=0.010)以及IgG水平(OR=0.153,P=0.020)均是带状疱疹后遗皮肤瘢痕的独立危险因素。结论:带状疱疹患者后遗皮肤瘢痕的发生率较高,应加强对年纪较大且伴随糖尿病患者的临床管理,注重对皮损部位的治疗,同时提升免疫球蛋白水平,以降低带状疱疹后遗皮肤瘢痕的形成。Objective To analyze the occurrence of skin scar after herpes zoster and its related influencing factors.Methods A total of 185 patients with herpes zoster who were treated in the author's hospital from April 2021 to October 2022 were selected as the research object.Data such as gender,age,previous medical history,severity,and location of the disease were collected.The patients were followed up for 6 months after the blisters subsided,and were divided into scar group and normal group according to the occurrence of skin scars.The risk factors of skin scar were analyzed by multi-factor Logistics.Results Finally,46 patients had skin scars,139 patients did not have skin scars,and the incidence of post-herpes zoster skin scars was 24.86%.The age and skin area of scar group were higher than that of normal group,the levels of serum IgA,IgG and IgM were lower than those of normal group,the proportion of herpes zoster on the face,the proportion of scab removal and the proportion of diabetes mellitus were higher than those of normal group(P<0.05).Multivariate Logistics regression analysis showed that age(OR=2.095,P=0.045),diabetes(OR=3.442,P=0.046),lesional extent(OR=1.467,P=0.010)and IgG level(OR=0.153,P=0.020)were all the independent risk factors for skin scar after herpes zoster.Conclusion The incidence of post-herpes zoster skin scar is high in patients with herpes zoster.Clinical management of older patients with diabetes should be strengthened,and the treatment of the skin lesion should be emphasized,while the level of immunoglobulin should be increased to reduce the formation of post-herpes zoster skin scar.

关 键 词：带状疱疹 后遗症 皮肤瘢痕 危险因素分析 

分 类 号：R752.1[医药卫生—皮肤病学与性病学]