短药蒲桃叶子的化学成分研究  

Studies on the chemical constituents of the leaves of Syzygium brachyantherum

作　　者：卯升丹 许文[1] 刘东豪 贺元彪 赵勇[1] MAO Shengdan;XU Wen;LIU Donghao;HE Yuanbiao;ZHAO Yong(Faculty of Chemistry and Chemical Engineering,Yunnan Normal University,Kunming 650500,Yunnan,China)

机构地区：[1]云南师范大学化学化工学院,云南昆明650500

出　　处：《云南大学学报（自然科学版）》2024年第4期759-764,共6页Journal of Yunnan University(Natural Sciences Edition)

基　　金：国家自然科学基金(35160098).

摘　　要：利用正反相硅胶柱色谱和Sephadex LH-20凝胶柱色谱等分离技术对短药蒲桃(Syzygium brachyantherum)叶子部分化学成分进行研究,运用NMR波谱技术和文献对照鉴定其结构,从中分离鉴定了10个化合物,分别为3β,23-O-isopropylidenyl-2a,19a-dihydroxy-urs-12-en-28-oic acid(1)、hyptaic acid B(2)、科罗索酸(3)、软木三萜酮(4)、表木栓醇(5)、粘霉烯醇(6)、daucosterol(7)、(7R,8S)-3,5'-dimethoxy-4',7-epoxy-8,3'-neolignane-5,9,9'-triol(8)、没食子酸甲酯(9)和β-芹子烯(10).其中,化合物1为新化合物,可能是在分离过程中由化合物2与丙酮形成的3β,23-缩酮,所有化合物均首次从短药蒲桃中分离得到.Various separation techniques such as normal and adverse silica gel and Sephadex LH-20 gel column chramatography were used to investigate the chemical constituents from the leaves of Syzygium brachyantherum.In result,ten compounds,including 3β,23-O-isopropylidenyl-2a,19a-dihydroxy-urs-12-en-28-oic acid(1),hyptaic acid B(2),corosolic acid(3),friedelin(4),friedelan-3β-ol(5),3β-hydroxy-5-glutinene(6),daucosterol(7),(7R,8S)-3,5'-dimethoxy-4',7-epoxy-8,3'-neolignane-5,9,9'-triol(8),methyl gallate(9)andβ-selinene(10)were isolated and determined and their structures were identified by NMR spectroscopic data and comparison with values reported.Among them,compound 1 was a new ketal produced by 2 and acetone during isolation.All compounds were isolated from S.brachyantherum for the first time.

关 键 词：桃金娘科 短药蒲桃 三萜 

分 类 号：R284.1[医药卫生—中药学]