Robust neutralization of SARS-CoV-2 variants including JN.1 and BA.2.87.1 by trivalent XBB vaccine-induced antibodies  

作　　者：Xun Wang Shujun Jiang Wentai Ma Yanliang Zhang Pengfei Wang 

机构地区：[1]Shanghai Pudong Hospital,Fudan University Pudong Medical Center,State Key Laboratory of Genetic Engineering,MOE Engineering Research Center of Gene Technology,School of Life Sciences,Shanghai Institute of Infectious Disease and Biosecurity,Fudan University,Shanghai,China [2]Department of Infectious Diseases,Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine,Nanjing Research Center for Infectious Diseases of Integrated Traditional Chinese and Western Medicine,Nanjing,Jiangsu,China [3]Beijing Institute of Genomics,Chinese Academy of Sciences,University of Chinese Academy of Sciences and China National Center for Bioinformation,Beijing,China

出　　处：《Signal Transduction and Targeted Therapy》2024年第6期2359-2361,共3页信号转导与靶向治疗（英文）

基　　金：supported by funding from the National Natural Science Foundation of China(32270142 to P.W.);the Shanghai Rising-Star Program(22QA1408800 to P.W.);the Program of Science and Technology Cooperation with Hong Kong region,Macao region,and Taiwan region(23410760500 to P.W.);Nanjing Research Center for Infectious Diseases of Integrated Traditional Chinese and Western Medicine(YBZX2022 to Y.Z.);NATCM’s Project of High-level Construction of Key TCM Disciplines;support from AI for Science project of Fudan University(XM06231724);Open Research Fund of State Key Laboratory of Genetic Engineering,Fudan University(No.SKLGE-2304);Xiaomi Young Talents Program.

摘　　要：Dear Editor,The rapid and widespread transmission of SARS-CoV-2 has led to the emergence of multiple variants of concern(VOCs),most notably the Omicron variant,which continues to evolve and diversify into a range of sub-lineages.Our previous research has shown that these Omicron sub-lineages,spanning BA.1-BA.2.86,have been evolving to exhibit increased neutralization escape capabilities.

关 键 词：evolve NEUTRALIZATION VARIANTS 

分 类 号：R186[医药卫生—流行病学] R373[医药卫生—公共卫生与预防医学]