潮气呼吸肺功能和过敏原检测预测喘息性肺炎患儿再次喘息的价值  

The Value of Tidal Respiratory Lung Function and Allergen Testing in Predicting Re-aspiration in Children with Wheezing Pneumonia

作　　者：朱冠兰 黄剑飞 梁修业 李雯菁 ZHU Guanlan;HUANG Jianfei;LIANG Xiuye;LI Wenjing(Department of Pediatrics,Nanning Wuming District Maternal and Child Health Hospital,Nanning 530100,Guangxi Zhuang Autonomous Region,China)

机构地区：[1]南宁市武鸣区妇幼保健院儿科,广西南宁530100

出　　处：《系统医学》2024年第12期14-16,20,共4页Systems Medicine

基　　金：南宁市武鸣区科学研究与技术开发计划项目(20210119)。

摘　　要：目的 研究潮气呼吸肺功能、体外过敏原检测、个人相关资料预测喘息性肺炎患儿再次发生喘息的价值。方法 回顾性选取武鸣区妇幼保健院儿科于2021年1月—2023年3月收治的喘息性肺炎的200例患儿的临床资料,根据是否发生再次喘息分为再次喘息组(124例)、无再次喘息组(76例)。分析潮气呼吸肺功能和过敏原检测、个人相关资料对再次喘息的预测价值。结果 Logistic回归分析表明,个人过敏史、家族过敏史、生活环境吸烟、吸入过敏原阳性是再次喘息的独立危险因素(OR=3.154、2.273、1.993、3.322,P均<0.05),而达峰时间比、达峰容积比是再次喘息的独立保护因素(OR=0.937、0.921,P均<0.05)。个人过敏史、家族过敏史、生活环境吸烟、吸入过敏原阳性、达峰时间比、达峰容积比预测再次喘息的AUC分别为0.743、0.624、0.785、0.804、0.841、0.862。结论 个人过敏史、家族过敏史、生活环境吸烟、吸入过敏原阳性是再次喘息的独立危险因素,达峰时间比、达峰容积比对再次喘息发生有保护作用,对预测发生再次喘息有一定的预测意义。Objective To study the value of tidal respiratory lung function,in vitro allergen testing,and personal related data in predicting re-aspiration in children with wheezing pneumonia.Methods The clinical data of 200 children with wheezing pneumonia admitted to the Department of Pediatrics of Wuming District Maternal and Child Health Hospital from January 2021 to March 2023 were retrospectively selected.They were categorized into reaspiration group(124 cases) and no re-aspiration group(76 cases) according to whether re-aspiration occurred or not.Analyzed the predictive value of tidal respiratory lung function,allergen testing,and personal related information for re-aspiration.Results Logistic regression analysis showed that personal history of allergy,family history of allergy,smoking in the living environment,and positive inhalation allergens were independent risk factors for re-aspiration(OR=3.154,2.273,1.993,3.322,all P<0.05),whereas the peak time ratio and peak volume ratio were independent protective factors for re-aspiration(OR=0.937,0.921,both P<0.05).The AUC of personal allergy history,family allergy history,living environment smoking,positive inhalation allergens,peak time ratio,and peak volume ratio for reaspiration were 0.743,0.624,0.785,0.804,0.841,and 0.862,respectively.Conclusion Personal history of allergy,family history of allergy,smoking in the living environment,and positive inhalation allergens were independent risk factors for re-aspiration.Peak time ratio and peak volume ratio had a protective effect on the occurrence of reaspiration,and were predictive of the occurrence of re-aspiration.

关 键 词：婴幼儿 喘息 潮气呼吸肺功能 过敏原检测 

分 类 号：R725.6[医药卫生—儿科]