血清铁蛋白、红细胞参数及红细胞形态在孕妇缺铁性贫血病情评估中的应用  

Application of Serum Ferritin,Erythrocyte Parameters and Erythrocyte Morphology in the Assessment of Iron Deficiency Anemia in Pregnant Women

作　　者：朱强[1] 魏国[1] 夏欢 ZHU Qiang;WEI Guo;XIA Huan(Sishui County People's Hospital,Sishui 273200,Shandong,China)

机构地区：[1]泗水县人民医院,山东泗水273200

出　　处：《系统医学》2024年第12期141-144,共4页Systems Medicine

摘　　要：目的 探究血清铁蛋白(Serum Ferritin,SF)、红细胞参数及红细胞形态在评估孕妇缺铁性贫血中的作用。方法 回顾性选取2022年1—12月泗水县人民医院收治的76例贫血孕妇的临床资料,以其贫血类型分为缺铁性贫血组(37例)、非缺血性贫血(39例),选同期42例常规筛查孕妇(无贫血)作为健康组;比较3组SF、红细胞参数水平[红细胞平均体积(Mean Corpuscular Volume,MCV)、红细胞平均血红蛋白量(Mean Corpuscular Hemoglobin,MCH)、红细胞(Red Blood Cell,RBC)、红细胞体积分布宽度(Red Blood Cell Volume Distribution Width,RDW)、血红蛋白(Hemoglobin,Hb)、红细胞比容(Hematocrit,HCT)]及显微镜下红细胞形态。结果 缺铁性贫血组患者SF、MCV、MCH水平均较健康组低,RBC、RDW均较健康组高,差异有统计学意义(P均<0.05);缺铁性贫血患者MCV、MCH、SF水平较非缺铁性贫血组低,RBC、RDW水平较非缺铁性贫血组高,差异有统计学意义(P均<0.05)。非缺铁性贫血组Hb、HCT水平与缺铁性贫血组对比,差异无统计学意义(P均>0.05)。缺铁性贫血组异常形态红细胞占比为(9.62±2.03)%,较非缺铁性贫血组(67.19±6.78)%低,差异有统计学意义(t=49.570,P<0.05)。缺铁性贫血组中,轻度、中度、重度患者,其MCV、Hb、SF水平逐渐降低,差异有统计学意义(P<0.05);MCV、Hb、SF水平与缺铁性贫血程度负相关(r=-0.587、-0.591、-0.756,P均<0.001)。结论 贫血孕妇中,缺铁性贫血孕妇会出现红细胞参数、红细胞形态学及SF水平变化,且随缺铁性贫血加重,MCV、Hb、SF水平随之下降,考虑可将其作为患者病情评估指标。Objective To investigate the role of serum ferritin(SF),erythrocyte parameters and erythrocyte morphology in the evaluation of iron deficiency anemia in pregnant women.Methods Clinical data of seventy-six pregnant women with anemia admitted to Sishui County People's Hospital from January 2022 to December 2022 were retrospectively selected.According to the type of anemia,they were divided into iron deficiency anemia group(37 cases) and non-iron deficiency anemia(39 cases),and forty-two pregnant women with routine screening during the same period(no anemia) were selected as the healthy group.SF,erythrocyte parameters [mean corpuscular volume(MCV),mean corpuscular hemoglobin(MCH),red blood cell(RBC),red blood cell volume distribution width(RDW),hemoglobin(Hb),hematocrit(HCT)] and the morphology of red blood cells under microscope were compared among the 3 groups.Results The levels of SF,MCV and MCH in iron deficiency anemia group were lower than those in healthy group,and RBC and RDW were higher than those in healthy group,the differences were statistically significant(all P<0.05).The levels of MCV,MCH and SF in patients with iron deficiency anemia were lower than those in non-iron deficiency anemia group,and the levels of RBC and RDW were higher than those in non-iron deficiency anemia group,the differences were statistically significant(all P<0.05).There was no significant difference in Hb and HCT levels between the non-iron deficiency anemia group and the iron deficiency anemia group(both P>0.05).The proportion of abnormal red blood cells in iron deficiency anemia group was(9.62±2.03) %,which was lower than that in non-iron deficiency anemia group(67.19±6.78)%,and the difference was statistically significant(t=49.570,P<0.05).In the iron deficiency anemia group,the levels of MCV,Hb and SF in mild,moderate and severe patients were gradually decreased,and the differences were statistically significant(all P<0.05).The levels of MCV,Hb and SF were negatively correlated with the degree of iron deficiency anemia(r=-0.

关 键 词：缺铁性贫血 血清铁蛋白 红细胞参数 

分 类 号：R556.3[医药卫生—血液循环系统疾病]