定喘口服液联合重组人干扰素α-1b雾化吸入治疗小儿呼吸道合胞病毒感染患者临床研究  

Clinical Study on Stopping Asthma Oral Liquid Combined with Recombinant Human InterferonΑ-1b Nebulized Inhalation for Pediatric Respiratory Syncytial Virus Infection

作　　者：张慧军 冉锦花 李康 贾新莉 ZHANG Huijun;RAN Jinhua;LI Kang;JIA Xinli(Department of Pediatrics,Longnan City the First People's Hospital,Longnan,Gansu 746000;Department of Neonatology,Longnan City the First People's Hospital,Longnan,Gansu 746000)

机构地区：[1]陇南市第一人民医院普儿科,甘肃陇南746000 [2]陇南市第一人民医院新生儿科,甘肃陇南746000

出　　处：《智慧健康》2024年第11期23-25,共3页Smart Healthcare

摘　　要：目的探讨小儿呼吸道合胞病毒(RSV)感染患者实施定喘口服液联合重组人干扰素α-1b雾化吸入治疗的应用价值。方法选取2023年3—5月陇南市第一人民医院接诊的RSV感染患者80例,根据随机数字表法将其分为对照组(常规治疗,n=40)、观察组(常规治疗+定喘口服液联合重组人干扰素α-1b雾化吸入治疗,n=40)两组。比较两组治疗后的临床症状消失时间(咳嗽减轻时间、喘憋消失时间、体温复常时间)、治疗前后的生理指标(血氧饱和度、氧合指数)。结果观察组治疗后临床症状消失时间和生理指标水平优于对照组,组间差异均有统计学意义(P<0.05)。结论定喘口服液联合重组人干扰素α-1b雾化吸入治疗小儿呼吸道合胞病毒感染可有效改善患者临床症状和呼吸功能。Objective To analyze application value of stopping asthma oral liquid and recombinant human interferonα1b nebulization inhalation for pediatric respiratory syncytial virus(RSV)infection.Methods The paper chose 80 patients with RSV infection in Longnan City the First People's Hospital from March 2023 to May 2023,and divided them into control group(with routine treatment,n=40)and observation group(routine treatment+stopping asthma oral liquid combined with recombinant human interferonα1b nebulized inhalation,n=40)with random number table method.Clinical symptom disappearance time(cough relief time,wheezing disappearance time,body temperature recovery time)and physiological indicators were compared before and after treatment between two groups,including blood oxygen saturation(SpO2)and oxygenation index(OI).Results Time for clinical symptom disappearance and physiological index levels in observation group after treatment were higher than control group(P<0.05).Conclusion Combination of stopping asthma oral liquid and recombinant human interferonα1b nebulization inhalation therapy can improve clinical symptoms and respiratory function of children with respiratory syncytial virus infection effectively.

关 键 词：定喘口服液 小儿呼吸道合胞病毒 重组人干扰素Α-1B 免疫功能 

分 类 号：R725.6[医药卫生—儿科]