卡泊三醇联合窄谱中波紫外线治疗寻常型银屑病的临床分析  

Clinical Analysis of Carbotriol Combined with Narrowband Ultraviolet Therapy for Psoriasis Vulgaris

作　　者：高睿 武晓丽 王惠茹 郭赟常 GAO Rui;WU Xiaoli;WANG Huiru;GUO Yunchang(Dermatology Department,No.985 Hospital of the Joint Logistics Support Force of PLA,Taiyuan,Shanxi 030001)

机构地区：[1]中国人民解放军联勤保障部队第九八五医院皮肤科,山西太原030001

出　　处：《智慧健康》2024年第11期29-31,共3页Smart Healthcare

摘　　要：目的探究寻常型银屑病患者应用卡泊三醇联合窄谱中波紫外线治疗的作用。方法选取2021年4月—2023年4月本院收治的76例寻常型银屑病患者纳入研究。采用盲摸双色球法均分为实验组、参照组,每组38例。参照组行窄谱中波紫外线治疗,实验组加用卡泊三醇治疗。对比分析两组的皮损情况、不良反应发生情况及生活质量。结果实验组PASI评分低于参照组,组间差异有统计学意义(P<0.05);两组不良反应发生情况对比相当,差异无统计学意义(P>0.05);实验组生活质量评分低于参照组,组间差异有统计学意义(P<0.05)。结论经临床验证,卡泊三醇与窄谱中波紫外线联合治疗方案,能够有效缓解寻常型银屑病患者的皮损症状,同时未观察到明显的不良反应。该治疗方案的应用,有助于显著提高患者的生活质量。Objective To explore effect of Carbotriol combined with narrow-band ultraviolet radiation therapy for patients with psoriasis vulgaris.Methods The paper chose 76 patients with psoriasis vulgaris in our hospital from April 2021 to April 2023 for study,and evenly divided them into experimental group and reference group with blind touch dual color sphere method,38 cases in each group.Reference group was treated with narrowband ultraviolet therapy,while experimental group with additional treatment with cabotriol.Skin lesions,incidence of adverse reactions,and life quality was compared between two groups.Results PASI scores of experimental group were lower than control group(P<0.05).Incidence of adverse reactions in two groups was comparable(P>0.05).Life quality scores of experimental group were lower than control group(P<0.05).Conclusion Combination of cabotriol and narrowband ultraviolet therapy can improve skin lesions of patients with psoriasis vulgaris,without significant adverse reactions,and improve life quality of patients.

关 键 词：卡泊三醇 窄谱中波紫外线 寻常型银屑病 皮损情况 不良反应 生活质量 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]