静脉用蔗糖铁联合促红细胞生成素治疗维持性血液透析伴慢性肾性贫血患者的疗效  

Curative Effect of Intravenous Sucrose Iron Combined with Erythropoietin on Maintenance Hemodialysis Patients with Chronic Renal Anemia

作　　者：何嘉意 黄沛娟 HE Jiayi;HUANG Peijuan(Jiaoling County People's Hospital,Meizhou,Guangdong 514100)

机构地区：[1]蕉岭县人民医院,广东梅州514100

出　　处：《智慧健康》2024年第12期106-108,共3页Smart Healthcare

摘　　要：目的探究维持性血液透析伴慢性肾性贫血采取静脉用蔗糖铁配合促红细胞生成素的治疗效果。方法选取2021年1月—2023年8月本院收治的100例维持性血液透析伴慢性肾性贫血患者为研究对象,并随机分为对照组和观察组,每组50例。其中,对照组采用琥珀酸亚铁+促红细胞生成素,观察组采用静脉用蔗糖铁+促红细胞生成素。对两组患者的相关临床恢复指标进行比较。结果观察组治疗有效率高于对照组,组间差异有统计学意义(P<0.05)。治疗前,两组贫血指标差异无统计学意义(P>0.05);治疗后,两组贫血相关指标水平比治疗前均有提高,且观察组指标提高幅度更为显著,差异有统计学意义(P<0.05)。两组不良反应发生率差异不大,无统计学意义(P>0.05)。结论采用静脉用蔗糖铁配合促红细胞生成素联合方案对维持性血液透析慢性伴肾性贫血患者治疗的疗效明显,可改善患者的贫血水平,且不会增加不良反应。Objective To explore curative effect of intravenous sucrose iron combined with erythropoietin on chronic renal anemia for maintenance hemodialysis.Methods The paper chose 100 chronic renal anemia patients with maintenance hemodialysis admitted to our hospital from January 2021 to August 2023,and divided them into two groups randomly,with 50 cases in control group(treated with ferrous succinate+erythropoietin)and the other 50 cases in observation group(with intravenous sucrose iron+erythropoietin).Relevant clinical recovery indicators were compared between two groups.Results Total effective rate was 96.00%in observation group and 88.00%in control group,there was significant difference between two groups(P<0.05).Before treatment,difference in anemia indicators between two groups before treatment was not significant(P>0.05),while anemia indicators in observation group after treatment were significantly higher than before treatment(P<0.05).Incidence of adverse reactions in observation group and control group was 4.00%and 8.00%respectively,,there was not much difference between two groups,(P>0.05).Conclusion Combination therapy of intravenous sucrose iron and erythropoietin can achieve significant curative effect on maintenance hemodialysis patients with chronic renal anemia,can improve anemia level of patients without increasing adverse reactions.

关 键 词：维持性血液透析慢性伴肾性贫血 静脉用蔗糖铁 促红细胞生成素 

分 类 号：R692.5[医药卫生—泌尿科学] R556[医药卫生—外科学]