磷酸肌酸钠联合大剂量维生素C治疗小儿病毒性心肌炎的疗效观察  

Curative Effect Observation of Sodium Creatine Phosphate Combined with High-Dose Vitamin C in Treatment of Pediatric Viral Myocarditis

作　　者：何茸茸 刘晶晶 徐莉 HE Rongrong;LIU Jingjing;XU Li(Pediatric Department,Huachi County People's Hospital,Huachi,Gansu745600)

机构地区：[1]华池县人民医院儿科,甘肃华池745600

出　　处：《智慧健康》2024年第12期137-139,共3页Smart Healthcare

摘　　要：目的观察小儿病毒性心肌炎经过磷酸肌酸钠与大剂量维生素C联合治疗后的具体疗效。方法选取2020年1月—2023年1月本院收治的68例小儿病毒性心肌炎患者为观察对象,并按照随机数表法分为对照组(34例,常规对症治疗)和观察组(34例,采用磷酸肌酸钠+大剂量维生素C开展治疗),对比两组总临床疗效、心肌酶指标以及不良反应情况、心电图改善情况。结果观察组临床疗效比对照组明显更高,组间差异有统计学意义(P<0.05)。观察组LDH、CK以及CK-MB等心肌酶指标改善情况比对照组明显更好,组间差异有统计学意义(P<0.05)。观察组不良反应发生率低于对照组,组间差异有统计学意义(P<0.05)。观察组心电图改善优良率明显比对照组更高,组间差异有统计学意义(P<0.05)。结论小儿病毒性心肌炎患者经过磷酸肌酸钠与大剂量维生素C治疗后所取得疗效十分理想,可有效调节心肌酶,促进患儿尽快恢复,减少不良反应,值得推广。Objective To observe specific curative effect of combined sodium creatine phosphate and high-dose vitamin C on pediatric viral myocarditis.Methods The paper chose 68 pediatric patients with viral myocarditis from January 2020 to January 2023 as observation subjects,and divided them into two groups based on random number table method.Control group of 34 cases was treated with routine symptomatic treatment,while observation group of 34 cases with sodium creatine phosphate and high-dose vitamin C.Total clinical effect,myocardial enzyme indicators,adverse reactions,and electrocardiogram improvement were compared.Results Clinical effect of observation group was 94.1%,significantly higher than 73.5%in control group,comparison of effect was statistically significant(P<0.05).Improvement of LDH,CK,and CK-MB indicators in observation group was significantly better than control group,myocardial enzyme indicators in both groups were statistically significant(P<0.05).Incidence of adverse reactions in observation group was 5.9%,lower than20.9%in control group.There was significant difference between the groups(P<0.05).Improvement rate of electrocardiogram in observation group was 94.1%,significantly higher than 76.4%in control group.Data comparison showed statistical significance(P<0.05).Conclusion Sodium creatine phosphate and high-dose vitamin C can achieve ideal curative effect for pediatric viral myocarditis patients,can regulate myocardial enzyme indicators,promote rapid recovery,reduce adverse reactions effectively,which is worthy of promotion.

关 键 词：小儿患者 病毒性心肌炎 磷酸肌酸钠 维生素C 治疗效果 

分 类 号：R725.4[医药卫生—儿科]