不同孕期妇女甲状腺功能改变与伴随症的关系探讨  

Relationship Exploration Between Changes in Thyroid Function and Comorbidities of Pregnant Women At Different Stages

作　　者：赵志艺 段炼 ZHAO Zhiyi;DUAN Lian Changzhi(Medical College Nuclear Medicine Department,Changzhi Medical College Affiliated Peace Hospital,Shanxi,Changzhi 046000)

机构地区：[1]长治医学院/长治医学院附属和平医院核医学科,山西长治046000

出　　处：《智慧健康》2024年第14期64-67,共4页Smart Healthcare

摘　　要：目的 探讨不同孕期妇女甲状腺激素变化情况,并依据甲状腺激素水平对甲状腺功能进行分类,分析甲状腺功能对妊娠伴随症的影响。方法 选取2020年1月—2021年6月在本院建档的正常妊娠女性406例作为研究对象,收集妊娠期女性的相关临床信息和甲状腺功能检测结果,以不同孕期和年龄段进行分组,对不同组别甲状腺功能和伴随症发生进行对比分析。结果 随着孕期增长,游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)呈降低趋势,促甲状腺激素(TSH)呈增长趋势,各组间具有统计学差异(P<0.05);孕早期(T1)出现甲状腺功能异常的情况要高于孕中期(T2)和孕晚期(T3)(P<0.05),甲状腺功能异常情况中甲减组较甲功正常组、甲亢组发生伴随症的比例高(P<0.05);T3期30岁以上孕妇更易出现伴随症。结论 孕妇甲状腺功能异常会引起不良伴随症的发生,其中甲减是更易导致不良妊娠的一个因素,临床需要根据甲状腺功能情况及时干预,以期提高妊娠质量。Objective To explore changes in thyroid hormones of women at different stages of pregnancy,classify thyroid function based on thyroid hormone levels,and analyze effect of thyroid function on pregnancy complications.Methods The paper reviewed and analyzed 406 normal pregnant women registered in our hospital from January 2020 to June 2021 as research subjects,collected their clinical information and thyroid function test results,and divided them into groups according to different pregnancy periods and age,compared and analyzed thyroid function and incidence of complications of different groups.Results Free triiodothyronine(FT3)and free thyroxine(FT4)showed a decreasing trend as pregnancy progressed,while thyroid stimulating hormone(TSH)showed an increasing trend,with statistical difference between the groups.Incidence of thyroid dysfunction in early pregnancy(T1)was higher than mid pregnancy(T2)and late pregnancy(T3).Incidence of comorbidities of thyroid dysfunction patients was higher in hypothyroidism group than normal and hyperthyroidism groups,Pregnant women at T3 stage and over 30 were likely to develop comorbidities.Conclusion Thyroid dysfunction of pregnant women may cause incidence of adverse complications,and hypothyroidism is one of factors to cause adverse pregnancy.Clinical intervention should be timely taken based on thyroid function to improve pregnancy quality.

关 键 词：妊娠妇女 甲状腺功能 伴随症 

分 类 号：R714.256[医药卫生—妇产科学]