新生儿耐甲氧西林金黄色葡萄球菌感染的临床分布及耐药研究  

Clinical Distribution and Drug Resistance of Methicillin-Resistant Staphylococcus Aureus Infection of Newborns

作　　者：孙肖依 SUN Xiaoyi(Laboratory Department,Changzhou City Maternal and Child Health Hospital,Changzhou,Jiangsu 213000)

机构地区：[1]常州市妇幼保健院检验科,江苏常州213000

出　　处：《智慧健康》2024年第17期32-34,38,共4页Smart Healthcare

摘　　要：目的分析新生儿耐甲氧西林金黄色葡萄球菌(MRSA)感染的临床分布及耐药情况。方法选取2020年1月—2023年1月本院收治的80例MRSA感染的新生儿作为研究对象,分析MRSA感染的临床分布及耐药性。结果在80例MRSA分布中,从标本类型来看,痰液47例(58.75%)、脓液11例(13.75%)、伤口分泌物10例(12.50%)、血液7例(8.75%)、尿液5例(6.25%);MRSA对青霉素G的耐药率最高(100.00%),其次为红霉素(76.25%)、克林霉素(68.75%)、四环素(48.75%)、苯唑西林(46.20%)及复方新诺明(11.50%),对其他药物的耐药率均在10.00%以下。结论新生儿MRSA感染在不同标本类型,特别是痰液中高发,且对多种抗生素表现出高度的耐药性。强调了针对高风险科室和不同标本类型需要加强监控,并突出合理使用抗生素的重要性。Objective To analyze clinical distribution and drug resistance of methicillin-resistant Staphylococcus aureus infection of newborns.Methods The paper chose 80 newborns with methicillinresistant Staphylococcus aureus(MRSA)infection in our hospital from January 2020 to January 2023 as research subjects,analyzed clinical distribution and drug resistance of MRSA infection.Results Among distribution of 80 cases MRSA,specimen types showed,there were 47 cases(58.75%)of sputum and 11 cases(13.75%)of pus,10 cases of wound secretions(12.50%),7 cases of blood(8.75%),and 5 cases of urine(6.25%).Resistance rate of MRSA to penicillin G was the highest(100%),followed by erythromycin(76.25%),clindamycin(68.75%),tetracycline(48.75%),oxacillin(46.20%),and compound sulfamethoxazole(11.50%).Resistance rate to other drugs was below 10.00%.Conclusion Neonatal methicillin-resistant Staphylococcus aureus(MRSA)infection can achieve high incidence in different specimen types,especially in sputum,and exhibit high resistance to multiple antibiotics.It is necessary to strengthen monitoring for high-risk departments and different specimen types,and highlight importance of rational use of antibiotics.

关 键 词：新生儿 耐甲氧西林金黄色葡萄球菌 临床分布 耐药性 

分 类 号：R446.5[医药卫生—诊断学] R722.1[医药卫生—临床医学]