81例肺隔离症患者的临床特征与不同治疗方法的网状Meta分析  

Network Meta-analysis of Clinical Characteristics of 81 Patients with Pulmonary Sequestration and Different Treatment Methods for Pulmonary Sequestration

作　　者：肖鑫华 黄宏[1] Xiao Xinhua;Huang Hong(Department of Respiratory and Critical Care Medicine,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China)

机构地区：[1]华中科技大学同济医学院附属同济医院呼吸与危重症医学科,武汉430030

出　　处：《华中科技大学学报（医学版）》2024年第4期519-527,共9页Acta Medicinae Universitatis Scientiae et Technologiae Huazhong

基　　金：十三五国家重点研发计划项目(No.2016YFC1304103)。

摘　　要：目的通过整合临床研究与网状Meta分析的结果,总结肺隔离症的临床特征,并比较不同治疗方法的优劣,为临床工作提供一定的参考信息。方法回顾性分析了华中科技大学同济医学院附属同济医院81例肺隔离症患者的临床特征,比较了开胸手术与胸腔镜手术的疗效。并检索相关文献进行网状Meta分析,比较介入治疗、胸腔镜手术和开胸手术治疗肺隔离症的疗效与安全性。结果单中心回顾性研究共纳入了81例患者,其中开胸组38例,胸腔镜组43例。在手术年限上,2016年前开胸组人数多于胸腔镜组,2017年以后开胸组人数少于胸腔镜组;胸腔镜组的术后住院天数短于开胸组(均P<0.05)。网状Meta分析最终纳入12篇文献,共591例患者。介入组手术时间短于胸腔镜组和开胸组;介入组术中出血量少于胸腔镜组和开胸组;胸腔镜组术中出血量少于开胸组;介入组术后住院天数少于胸腔镜组和开胸组;胸腔镜组的术后住院天数少于开胸组(均P<0.05)。结论与传统开胸手术和胸腔镜手术相比,介入治疗肺隔离症手术时间更短、术中出血量更少、术后住院天数更少。Objective To summarize the clinical characteristics of pulmonary sequestration by integrating the results of clinical research and network meta-analysis,and to compare the advantages and disadvantages of different treatment methods,so as to provide certain reference information for clinical work.Methods The clinical characteristics of 81 patients with pulmonary sequestration in Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology were retrospectively analyzed,and the efficacy of thoracotomy and thoracoscopic surgery was compared.Relevant literatures were retrieved for network meta-analysis to compare the efficacy and safety of interventional therapy,thoracoscopic surgery,and thoracotomy in the treatment of pulmonary sequestration.Results A total of 81 patients were included in the single-center retrospective study,including 38 in the thoracotomy group and 43 in the thoracoscopic group.In terms of surgical years,the number of patients in the thoracotomy group was more than that in the thoracoscopic group before 2016,and less than that in the thoracoscopic group after 2017(all P<0.05).The postoperative hospital stay in the thoracoscopic group was shorter than that in the thoracotomy group(both P<0.05).A total of 12 records involving 591 patients were included in the network meta-analysis.The operation time of the interventional group was shorter than that of the thoracoscopic group and the thoracotomy group.The intraoperative blood loss in the interventional group was less than that in the thoracoscopic group and the thoracotomy group.The intraoperative blood loss in the thoracoscopic group was less than that in the thoracotomy group.The postoperative hospital stay in the interventional group was shorter than that in the thoracoscopic group and the thoracotomy group.The postoperative hospital stay in the thoracoscopic group was shorter than that in the thoracotomy group(all P<0.05).ConclusionCompared with traditional thoracotomy and thoracoscopic surgery,intervention

关 键 词：肺隔离症 手术 介入治疗 网状Meta分析 

分 类 号：R655.3[医药卫生—外科学]