多房棘球绦虫感染的检测方法研究进展  

Advances in the detection methods of Echinococcus multilocularis infection in definitive hosts

作　　者：游杰 李立[1] 孙继文 詹舒懿 逯文颖 周蜓蜓 殷宏[1,2] 贾万忠 闫鸿斌[1] YOU Jie;LI Li;SUN Jiwen;ZHAN Shuyi;LU Wenying;ZHOU Tingting;YIN Hong;JIA Wanzhong;YAN Hongbin(State Key Laboratory for Animal Disease Control and Prevention/College of Veterinary Medicine of Lanzhou University/National Para-Reference Laboratory for Animal Echinococcosis/Gansu Province Research Center for Basic Disciplines of Pathogen Biology/Key Laboratory of Veterinary Parasitology of Gansu Province/Lanzhou Veterinary Research Institute,Chinese Academy of A gricultural Sciences,Lanzhou 730000,China;Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Disease,Yangzhou 225009,China)

机构地区：[1]中国农业科学院兰州兽医研究所兰州大学动物医学与生物安全学院动物疫病防控全国重点实验室国家动物包虫病专业实验室甘肃省病原生物学基础学科研究中心甘肃省动物寄生虫病重点实验室,甘肃兰州730000 [2]江苏省动物重要疫病与人兽共患病防控协同创新中心,江苏扬州225009

出　　处：《中国兽医科学》2024年第7期946-954,共9页Chinese Veterinary Science

基　　金：国家重点研发计划项目(2022YFD1302100);甘肃省科技重大专项(23ZDNA007,22ZD6NA001);国家肉牛牦牛产业技术体系项目(CARS-37);中国农业科学院科技创新工程项目(CAAS-ASTIP-2021-LVRI)。

摘　　要：棘球蚴病是由棘球绦虫的幼虫(中绦期)——棘球蚴引起的一类人兽共患寄生虫病。感染棘球绦虫的终末宿主(犬、狐狸等)是传染源,及时准确检测终末宿主感染状况是防控棘球蚴病的关键环节。本文综述了多房棘球绦虫感染的病原学、分子生物学和免疫学检测方法的研究进展,以期为终末宿主多房棘球绦虫感染的检测方法研究和试剂盒研发提供指导。Echinococcosis is a zoonotic parasitic disease caused by the larvae or metacestodes of Echinococcus spp.The definitive host(dogs,foxes,etc.)with Echinococcus spp.is the source of transmission,and timely and accurate detection of the infected host is the key to prevent and control the disease.In this study,etiological,molecular biological and immunological detection methods for E.multilocularis were reviewed,hoping to help for the development of novel detection methods and kits for the infection in the definitive host.

关 键 词：多房棘球绦虫 犬科动物 粪DNA 粪抗原 分子生物学检测 免疫学诊断 

分 类 号：S852.734[农业科学—基础兽医学]