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作 者:秦珊珊 聂鹏 QIN Shanshan;NIE Peng(Department of General Surgery,Jinan Seventh People's Hospital,Jinan 250101,Shandong,China;Department of Joint Surgery,Jinan Seventh People's Hospital,Jinan 250101,Shandong,China)
机构地区:[1]济南市第七人民医院普外科,山东济南250101 [2]济南市第七人民医院关节外科,山东济南250101
出 处:《中外医疗》2024年第18期5-8,共4页China & Foreign Medical Treatment
摘 要:目的分析低分子肝素联合气压治疗对预防外科术后患者下肢深静脉血栓形成的效果。方法前瞻性随机选取2022年1月—2023年12月济南市第七人民医院收治的500例手术患者为研究对象,按照随机数字表法将其分为对照组(n=250)、观察组(n=250),分别开展常规气压治疗、气压治疗与低分子肝素联合治疗,比较两组患者康复效果、下肢深静脉血栓形成发生率、凝血指标。结果观察组的康复有效率明显高于对照组,差异有统计学意义(P<0.05)。观察组下肢深静脉血栓形成发生率(0.80%)显著低于对照组(6.00%),差异有统计学意义(χ^(2)=10.291,P<0.05)。观察组凝血酶原时间、活化部分凝血活酶时间、凝血酶时间、纤维蛋白原均优于对照组,差异有统计学意义(P均<0.05)。结论低分子肝素与气压联合治疗在外科术后患者中具有非常显著的效果,能降低下肢深静脉血栓的发生率。Objective To analyze the effect of low molecular weight heparin combined with air pressure therapy on the prevention of deep venous thrombosis of lower limbs in patients after surgery.Methods 500 surgical patients admitted to the Seventh People's Hospital of Jinan from January 2022 to December 2023 were prospective randomly selected as the study subjects.They were divided into control group(n=250)and observation group(n=250),according to the ran-dom number table method.Conventional air pressure therapy,air pressure therapy and low molecular weight heparin combined therapy were carried out respectively.The rehabilitation effect,incidence of deep venous thrombosis and co-agulation indexes were compared between the two groups.Results The effective rate of rehabilitation in the observa-tion group was significantly higher than that in the control group,the difference was statistically significant(P<0.05).The incidence of lower extremity deep venous thrombosis in the observation group(0.80%)was significantly lower than that in the control group(6.00%),and the difference was statistically significant(χ^(2)=10.291,P<0.05).The pro-thrombin time,activated partial thromboplastin time,thrombin time and fibrinogen in the observation group were bet-ter than those in the control group,and the differences were statistically significant(all P<0.05).Conclusion The com-bination of low molecular weight heparin and air pressure therapy has a definite effect on postoperative patients and can significantly reduce the incidence of deep venous thrombosis.
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