肺表面活性物质联合经鼻持续气道正压通气治疗新生儿呼吸窘迫综合征的效果分析  

Analysis on Effect of Pulmonary Surfactant Combined with Nasal Continuous Positive Airway Pressure in Treatment of Neonatal Respiratory Distress Syndrome

作　　者：孙艳 Sun Yan(Department of Pediatrics,The First People's Hospital of Lanzhou City,Lanzhou 730050,Gansu Province,China)

机构地区：[1]兰州市第一人民医院儿科,甘肃兰州730050

出　　处：《中国社区医师》2024年第17期38-40,共3页Chinese Community Doctors

摘　　要：目的:分析新生儿呼吸窘迫综合征患者应用肺表面活性物质(PS)协同经鼻持续气道正压通气(NCPAP)治疗的效果。方法:将兰州市第一人民医院收治的66例新生儿呼吸窘迫综合征患儿(于2020年1月—2023年1月收入)作为观察对象,使用随机抽样法分组,每组33例。对照组、观察组分别接受NCPAP、PS联合NCPAP治疗。评估两组治疗效果。结果:相较于对照组,观察组治疗有效率更高(P<0.05);相较于对照组,观察组动脉血二氧化碳分压更低,动脉血氧分压更高(P<0.05);两组并发症发生率无差异(P>0.05);相较于对照组,观察组氧疗时间、NCPAP时间、住院时间更短(P<0.05);相较于对照组,观察组呼气终末正压、吸入氧浓度更低,氧合指数更高(P<0.05)。结论:PS结合NCPAP治疗新生儿呼吸窘迫综合征的效果良好,能够进一步改善血气指标,减少并发症,纠正缺氧症状,促进患儿康复。Objective:Analyze and evaluate the efficacy of pulmonary surfactant(PS)combined with nasal continuous positive airway pressure(NCPAP)in the diagnosis and treatment of neonatal respiratory distress syndrome.Method:A study was conducted on 66 cases of neonatal respiratory distress syndrome in our hospital,all of whom had income from January 2020 to January 2023.They were randomly divided into two groups,with 33 cases in each group.The control group and the observation group received NCPAP,NCPAP and PS treatment,respectively,and the diagnostic and therapeutic effects were evaluated.Result:Compared with the effective rate of treatment,the data of the observation group was higher than that of the control group(P<0.05).Compared with PaCO_(2),the data of the observation group was lower than that of the control group.Compared with PaO_(2),the data of the observation group was higher than that of the control group(P<0.05);There was no statistically significant difference in the incidence of complications between the groups(P>0.05);Comparing the oxygen therapy time and NCPAP time,the data of the observation group was lower than that of the control group.Comparing the positive end expiratory pressure and percentage of inhaled oxygen concentration,the number of data in the observation group was higher than that of the control group(P<0.05).Conclusion:The combination of PS and NCPAP can achieve maximum benefits in the treatment of neonatal respiratory distress syndrome,further improve blood gas indicators,reduce complications,correct hypoxia symptoms,and promote the recovery of the child.

关 键 词：新生儿 呼吸窘迫综合征 肺表面活性物质 经鼻持续气道正压通气 

分 类 号：R722.1[医药卫生—儿科]