不同剂量麻醉药在超高龄患者腰硬联合麻醉中的应用效果分析  

Analysis on Application Effect of Different Doses of Anesthetics in Combined Spinal-Epidural Anesthesia of Ultra-Elderly Patients

作　　者：苏海文[1] 李海芳[1] 高路明 姜文霞 Su Haiwen;Li Haifang;Gao Luming;Jiang Wenxia(Qingdao Third People's Hospital,Qingdao 266041,Shandong Province,China;Qingdao Hospital of Traditional Chinese Medicine(Qingdao Hiser Hospital),Qingdao 266033,Shandong Province,China)

机构地区：[1]青岛市第三人民医院,山东青岛266041 [2]青岛市中医医院(青岛市海慈医院),山东青岛266033

出　　处：《中国社区医师》2024年第18期65-67,共3页Chinese Community Doctors

摘　　要：目的:分析不同剂量麻醉药在超高龄患者腰硬联合麻醉中的应用效果。方法:选取2019年6月—2020年8月于青岛市第三人民医院行腰硬联合麻醉手术的患者96例作为研究对象,采用随机数字表法分为观察组和对照组,各48例。观察组给予麻醉药2.0 mL,对照组给予麻醉药1.5 mL。比较两组麻醉效果、血流动力学指标、疼痛情况、不良反应发生情况。结果:观察组完全阻滞时间、麻醉起效时间早于对照组,差异有统计学意义(P<0.001)。麻醉前,两组DBP、SBP、HR比较,差异无统计学意义(P>0.05);手术切皮时、手术完成时、术后1 h,两组DBP、SBP、HR高于麻醉前,但观察组低于对照组,差异有统计学意义(P<0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论:相较于低剂量麻醉药,高剂量麻醉药在超高龄患者腰硬联合麻醉中的应用效果更好,有助于提高麻醉效果,保持患者术中生命体征平稳,且安全性较好。Objective:To analyze the application effect of different doses of anesthetics in combined spinal-epidural anesthesia for ultra-elderly patients.Methods:A total of 96 patients who underwent combined spinal-epidural anesthesia surgery in Qingdao Third People's Hospital from June 2019 to August 2020 were selected as the study subjects.They were divided into observation group and control group according to random number table method,with 48 cases in each group.The observation group was given 2.0 mL anesthetic,and the control group was given 1.5 mL anesthetic.The anesthesia effect,hemodynamic indexes,pain and adverse reactions were compared between the two groups.Results:The complete block time and anesthesia onset time in the observation group were earlier than those in the control group,and the difference was statistically significant(P<0.001).Before anesthesia,there was no significant difference in DBP,SBP and HR between the two groups(P>0.05).At the time of surgical skin incision,at the end of the surgery and at 1 h after surgery,the DBP,SBP,and HR in the two groups were higher than those before anesthesia,but those indexes in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Compared with low-dose anesthetics,high-dose anesthetics have better application effect in combined spinal-epidural anesthesia for ultra-elderly patients,which is helpful to improve the anesthesia effect,maintain the stable intraoperative vital signs of patient,and have good safety.

关 键 词：超高龄 腰硬联合麻醉 麻醉药 剂量 

分 类 号：R614[医药卫生—麻醉学]