灯盏乙素通过调控TGF-β信号通路抑制脏器纤维化的研究进展  

Research progress of inhibiting organ fibrosis by regulating TGF-βsignaling pathway

作　　者：李鹏宇 夏瑜(综述) 李飞(审校)[2] Li Pengyu;Xia Yu;Li Fei(The First Clinical Medical College,Kunming Medical University,Yunnan Province,Kunming 650500,China;不详)

机构地区：[1]昆明医科大学第一临床医学院,昆明650500 [2]昆明医科大学

出　　处：《疑难病杂志》2024年第8期1021-1024,共4页Chinese Journal of Difficult and Complicated Cases

基　　金：云南省科技厅科技计划项目(202101AY070001-040)。

摘　　要：灯盏乙素(SCU)在抑制脏器纤维化方面的研究取得了显著的进展,文章对灯盏乙素通过TGF-β信号通路在调控脏器纤维化中的作用机制进行深入探讨,并详述了灯盏乙素对肝、肺、心脏和肾等脏器纤维化的抑制效应,为揭示灯盏乙素在治疗脏器纤维化疾病中的机制提供了深刻的认识。In recent years,significant advancements have been made in the study of Scutellarin's role in inhibiting organ fibrosis.The article delves into the mechanisms by which Scutellarin regulates organ fibrosis through the TGF-βsignaling pathway.It provides a detailed discussion of Scutellarin's inhibitory effects on liver,lung,heart,and kidney fibrosis,offering profound insights into the mechanisms underlying Scutellarin's therapeutic potential in treating organ fibrosis diseases.

关 键 词：灯盏乙素 转化生长因子-β信号通路 脏器纤维化 

分 类 号：R453[医药卫生—治疗学]