Impact of depression on in-hospital outcomes for adults with type 2 myocardial infarction:A United States population-based analysis  

作　　者：Sivaram Neppala Himaja Dutt Chigurupati Shaylika Chauhan Mrunal Teja Chinthapalli Rupak Desai 

机构地区：[1]Department of Internal Medicine,University of Texas at San Antonio,San Antonio,TX 78249,United States [2]Department of Internal Medicine,New York Medical College at Saint Michael’s Medical Center,Newark,NJ 07102,United States [3]Department of Internal Medicine,Geisinger Health System,Wikes-Barre,PA 18702,United States [4]Department of Internal Medicine,Mayo Clinic,Rochester,MN 55905,United States [5]Independent Researcher,Atlanta,GA 30079,United States

出　　处：《World Journal of Cardiology》2024年第7期412-421,共10页世界心脏病学杂志（英文版）（电子版）

摘　　要：BACKGROUND Type 2 myocardial infarction(T2MI)is an ischemic myocardial injury in the context of oxygen supply/demand mismatch in the absence of a primary coronary event.However,though there is a rising prevalence of depression and its potential association with type 1 myocardial infarction(T1MI),data remains nonexistent to evaluate the asso-ciation with T2MI.AIM To identify the prevalence and risk of T2MI in adults with depression and its impact on the in-hospital outcomes.METHODS We queried the National Inpatient Sample(2019)to identify T2MI hospitalizations using Internal Classification of Diseases-10 codes in hospitalized adults(≥18 years).In addition,we compared sociodemographic and comorbidities in the T2MI cohort with vs without comorbid depression.Finally,we used multivariate regression analysis to study the odds of T2MI hospitalizations with vs without depression and in-hospital outcomes(all-cause mortality,cardiogenic shock,cardiac arrest,and stroke),adjusting for confounders.Statistical significance was RESULTS There were 331145 adult T2MI hospitalizations after excluding T1MI(median age:73 years,52.8%male,69.9%white);41405(12.5%)had depression,the remainder;289740 did not have depression.Multivariate analysis revealed lower odds of T2MI in patients with depression vs without[adjusted odds ratio(aOR)=0.88,95%confidence interval(CI):0.86-0.90,P=0.001].There was the equal prevalence of prior MI with any revascularization and a similar prevalence of peripheral vascular disease in the cohorts with depression vs without depression.There is a greater prevalence of stroke in patients with depression(10.1%)vs those without(8.6%).There was a slightly higher prevalence of hyperlipidemia in patients with depression vs without depression(56.5%vs 48.9%),as well as obesity(21.3%vs 17.9%).There was generally equal prevalence of hypertension and type 2 diabetes mellitus in both cohorts.There was no significant difference in elective and non-elective admissions frequency between cohorts.Patients with depression vs wit

关 键 词：Type 2 myocardial infarction DEPRESSION Major adverse cardiovascular events Mortality Stroke Cardiac arrest OUTCOMES 

分 类 号：R542.22[医药卫生—心血管疾病] R749[医药卫生—内科学]