Evolution of heart transplant donor characteristics in the 21st century: A United States single center’s experience  

作　　者：Alexander M Spring Christiana Gjelaj Shivank Madan Snehal R Patel Omar Saeed Sandhya Murthy Yogita Rochlani Daniel B Sims Sasha Vukelic Stephen J Forest Jamil F Borgi Daniel J Goldstein Ulrich P Jorde 

机构地区：[1]Montefiore-Einstein Center for Heart and Vascular Care,Montefiore Medical Center,Albert Einstein College of Medicine,Bronx,NY 10467,United States [2]Division of Cardiothoracic Surgery,Tulane University,New Orleans,LA 70112,United States

出　　处：《World Journal of Transplantation》2024年第3期22-29,共8页世界移植杂志

摘　　要：Despite a record setting number of heart transplants performed annually,the national donor shortage continues to plague transplant teams across the United States.Here we describe the barriers to adaptation of numerous“non-traditional”orthotopic heart transplant donor characteristics including donors with hepatitis C virus,those meeting criteria for donation after cardiac death,donors with coronavirus disease 19 infection,donors with the human immunodeficiency virus,and grafts with left ventricular systolic dysfunction.Our center’s objective was to increase our transplant volume by expanding our donor pool from“traditional”donors to these“non-traditional”donors.We detail how medical advances such as certain laboratory studies,pharmacologic interventions,and organ care systems have allowed our center to expand the donor pool thereby increasing transplantation volume without adverse effects on outcomes.

关 键 词：Orthotopic heart transplantation Hepatitis C virus COVID-19 Left ventricular systolic dysfunction Human immunodeficiency virus Donation after cardiac death 

分 类 号：R654.2[医药卫生—外科学]