Higher ambient temperatures may worsen obstructive sleep apnea:A nationwide smartwatch-based analysis of 6.2 million person-days  

作　　者：Anni Li Qingli Zhang Yuan Yao Xinlei Zhu Cong Liu Yutao Guo Haidong Kan Renjie Chen 

机构地区：[1]School of Public Health,Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment,Fudan University,Shanghai 200032,China [2]Ministry of Education-Shanghai Key Laboratory of Children’s Environmental Health,Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200092,China [3]Department of Pulmonary Vessel and Thrombotic Disease,Sixth Medical Center,Chinese PLA General Hospital,Beijing 100048,China [4]Institute for Hospital Management Research,Chinese PLA General Hospital,Beijing 100048,China [5]Children’s Hospital of Fudan University,National Children’s Medical Center,Shanghai 201102,China [6]School of Public Health,Hengyang Medical School,University of South China,Hengyang 421001,China

出　　处：《Science Bulletin》2024年第13期2114-2121,共8页科学通报（英文版）

基　　金：supported by the Shanghai Municipal Science and Technology Major Project(2023SHZDZX02);Shanghai B&R Joint Laboratory Project(22230750300);Shanghai International Science and Technology Partnership Project(21230780200);the Shanghai Committee of Science and Technology(21TQ015);the Shanghai 3-year Public Health Action Plan(GWVI-11.2-YQ32).

摘　　要：Obstructive sleep apnea(OSA)is a serious type of sleep disorder that can lead to cardiometabolic and neurocognitive diseases.We utilized smart device-based photoplethysmography technology to collect sleep data from the Chinese population from 2019 to 2022.Distributed lag nonlinear models combined with a generalized nonlinear model or a linear mixed effects model were used to investigate the shortterm associations between daily temperature and indicators of OSA severity.We included a total of 6,232,056 d of sleep monitoring data from 51,842 participants with moderate to severe risk of OSA from 313 Chinese cities.The relationships between ambient temperature and OSA exacerbation,apneahypopnea index(AHI),and minimum oxygen saturation(MinSpO_(2))were almost linear and present only on the same day.Higher temperatures were associated with a greater risk of OSA exacerbation,with an 8.4%(95%confidence interval(CI):7.6%–9.3%)increase per 10℃increase in temperature.A 10℃increase in daily temperature corresponded to an AHI increase of 0.70 events/h(95%CI:0.65–0.76)and a MinSpO_(2)decrease of 0.18%(95%CI:0.16%–0.19%).Exposure to elevated temperatures during the night can also lead to adverse effects.The effects of higher temperatures on OSA severity were stronger among men,participants with a body mass index24 kg/m2,those aged 45 years and older,individuals with a history of hypertension and diabetes,and during the cold season.This large-scale,nationwide,longitudinal study provides robust evidence suggesting that higher ambient temperatures may immediately worsen OSA.

关 键 词：Obstructive sleep apnea Temperature Apnea-hypopnea index Oxygen saturation Smart device 

分 类 号：R766.43[医药卫生—耳鼻咽喉科]