全身麻醉对非心脏外科术后患者认知功能的影响研究  

Study on the Impact of General Anesthesia on Cognitive Function in Postoperative Patients Undergoing Non-cardiac Surgery

作　　者：胡玉翠 王玲玲 杨仁猛 Hu Yucui;Wang Lingling;Yang Renmeng(Anesthesiology Department,Shandong Rehabilitation Hospital,Jinan,Shandong 250109)

机构地区：[1]山东省康复医院麻醉科,山东济南250109

出　　处：《科技与健康》2024年第14期9-12,共4页Technology and Health

摘　　要：探究全身麻醉对非心脏外科术后患者认知功能的影响。以2019年1月-2019年12月山东省康复医院收治的40例非心脏外科手术患者为研究对象,按照随机抽样的方法将患者均分为对照组和观察组两组。其中对照组注射利多卡因与甲基酸罗哌卡因,观察组进行全身麻醉,并给予患者相应的诱导剂(咪达唑仑、舒芬太尼、苯磺顺阿曲库铵和异丙酚)。对比两组患者认知障碍发生率和MMSE评分。结果显示,观察组患者的认知障碍发生率与对照组相比,无统计学差异(P>0.05);观察组患者MMSE评分的改善程度与对照组相比,无统计学差异(P>0.05)。研究发现,全身麻醉对非心脏术后患者认知功能的影响因个体而异,应选用对认知功能影响小的麻醉药物,并加强围术期护理和术后康复治疗,制订个性化麻醉方案以保护患者的神经功能。Exploring the impact of general anesthesia on cognitive function in postoperative patients undergoing non cardiac surgery.Forty non cardiac surgical patients admitted to Shandong Rehabilitation Hospital from January 2019 to December 2019 were selected as the research subjects.The patients were randomly divided into a control group and an observation group.The control group was injected with lidocaine and ropivacaine methyl acid,while the observation group received general anesthesia and corresponding inducers(midazolam,sufentanil,phenylsulfonylurea,and propofol).Compare the incidence of cognitive impairment and MMSE scores between two groups of patients.The results showed that there was no statistically significant difference in the incidence of cognitive impairment between the observation group and the control group(P>0.05);There was no statistically significant difference(P>0.05)in the improvement of MMSE scores between the observation group and the control group.Research has found that the impact of general anesthesia on cognitive function in non cardiac postoperative patients varies from individual to individual.Anesthetic drugs with minimal impact on cognitive function should be selected,and perioperative care and postoperative rehabilitation treatment should be strengthened.Personalized anesthesia plans should be developed to protect patients’neurological function.

关 键 词：全身麻醉 非心脏外科手术 术后认知功能 影响因素 研究进展 

分 类 号：R654.1[医药卫生—外科学]