慢性前列腺炎/慢性盆腔疼痛综合征患者精浆成分和相应精子质量改变的研究进展  

Changes in seminal plasma composition and corresponding sperm quality in patients with chronic prostatitis/chronic pelvic pain syndrome:Progress in studies

作　　者：徐文龙(综述) 马文明(综述) 梁朝朝(审校)[1] XU Wen-long;MA Wen-ming;LIANG Chao-zhao(Department of Urology/Anhui Medical University Research Institute of Urology/Key Laboratory of Anhui Province for Urological and Andrological Diseases Research and Medical Transformation,The First Affiliated Hospital of Anhui Medical University,Hefei,Anhui 230022,China)

机构地区：[1]安徽医科大学第一附属医院泌尿外科/安徽医科大学泌尿外科研究所/泌尿男科疾病研究与医学转化安徽省重点实验室,安徽合肥230022

出　　处：《中华男科学杂志》2024年第5期444-449,共6页National Journal of Andrology

基　　金：国家自然科学基金面上项目(82370776)。

摘　　要：前列腺炎是前列腺三大常见疾病之一,此外分别是前列腺增生和前列腺癌。约50%的男性一生之中曾患前列腺炎。慢性前列腺炎/慢性盆腔疼痛综合征(CP/CPPS)患者中不育症的发生率显著高于正常患者,这主要与慢性前列腺炎患者精液成分的改变有关。本综述通过使用“慢性前列腺炎”、“慢性盆腔疼痛综合征”、“精子”、“精液”和“精浆”等关键词及术语,在PubMed和医学线检索了截至2024年之前发表的人类和动物研究的综述文章、临床试验和病例报告及相关引文。综合回顾了既往对于慢性前列腺炎与精浆变化及精子质量相关研究和调查,通过CP/CPPS患者前列腺液的成分的改变导致精浆成分发生变化的角度,讨论其对精子质量的影响。Prostatitis is one of the three most common prostate diseases in men,the other two being prostatic hyperplasia and prostate cancer,and about 50% of men worldwide have been attacked by prostatitis during their lives.The incidence of infertility is significantly higher in patients with chronic prostatitis/chronic pelvic pain syndrome(CP/CPPS)than in those without it,which is mainly attributed to the changed semen composition of the CP/CPPS patients.Using the key words chronic prostatitis,chronic pelvic pain syndrome,sperm,semen,and seminal plasma,we searched PubMed and Medical Lines online for originals,review articles,clin-ical trials,case reports and associated citations on humans and animals published up to 2024.We comprehensively reviewed the previ-ous studies and investigations relating chronic prostatitis,seminal plasma change and sperm quality,and discussed the impact of the change of semen composition on sperm quality.

关 键 词：慢性前列腺炎 慢性盆腔疼痛综合征 精浆 精子 锌离子 抗精子抗体 

分 类 号：R697.33[医药卫生—泌尿科学]