基于数据挖掘技术探究针刺治疗小脑共济失调的选穴规律  

Exploration of the Acupoint Selection Rules of Acupuncture for the Treatment of Cerebellar Ataxia Based on Data Mining Technology

作　　者：纵艳平 王茎[2] 曾永蕾[3] 郭锦晨 高兵 李凌基 ZONG Yan-Ping;WANG Jing;ZENG Yong-Lei;GUO Jin-Chen;GAO Bing;LI Ling-Ji(School of Acupuncture,Moxibustion and Tuina,Anhui University of Chinese Medicine,Hefei 230038 Anhui,China;Key Laboratory of Xin’an Medicine,Ministry of Education of Anhui University of Chinese Medicine,Hefei 230038 Anhui,China;Dept.of Oncology,The Second Affifiliated Hospital of Anhui University of Chinese Medicine,Hefei 230001 Anhui,China;School of Traditional Chinese Medicine,Anhui University of Chinese Medicine,Hefei 230038 Anhui,China)

机构地区：[1]安徽中医药大学针灸推拿学院,安徽合肥230038 [2]安徽中医药大学新安医学教育部重点实验室,安徽合肥230038 [3]安徽中医药大学第二附属医院肿瘤科,安徽合肥230001 [4]安徽中医药大学中医学院,安徽合肥230038

出　　处：《广州中医药大学学报》2024年第8期2099-2109,共11页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：国家自然科学基金面上项目(编号:81574084);安徽省教育厅重点资助项目(编号:KJ2021A0570,2023AH050796);安徽省重点研究与开发计划资助项目(编号:202004j07020045);新安医学教育部重点实验室开放基金资助项目(编号:2020xayx07);新安医学与中医药现代化研究所“揭榜挂帅”资助项目(编号:2023CXMMTCM022)。

摘　　要：【目的】应用数据挖掘技术探究针刺治疗小脑共济失调的选穴规律。【方法】以针刺治疗小脑共济失调的相关文献为检索内容,计算机检索中国知网期刊全文数据库(CNKI)、中国生物医学文献数据库(SinoMed)、万方学术期刊全文数据库(Wanfang)、维普中文科技期刊数据库(VIP)、美国生物医学信息检索系统(PubMed)等各大数据库。将文献中符合条件的腧穴录入Microsoft Excel 2021软件表格内,建立针刺治疗小脑共济失调的腧穴频次频率、归经、特定穴、分布部位等信息的数据库。采用SPSS Modeler 18.0 Apriori算法、SPSS Statistics 25.0及SPSS modeler 18.0 Web复杂网络对纳入的处方腧穴进行关联规则分析、Ward聚类分析并绘制树状图及高频腧穴与核心处方的Web网络图。【结果】(1)共收录文献93篇,其中,针刺处方117条,穴位172个,穴位使用总频次1199次;(2)腧穴使用频数位居前10位的分别是风池、足三里、合谷、百会、三阴交、太冲、曲池、阳陵泉、完骨、天柱;(3)使用频数位于前5位的经脉分别是足少阳胆经、督脉、足阳明胃经、手阳明大肠经、足太阳膀胱经;(4)腧穴使用部位选择主要以头面颈项部及下肢部为主;(5)特定穴的使用频数最高的是交会穴;(6)针刺治疗小脑共济失调的高频穴位是风池-完骨、风池-天柱和风池-天柱-完骨。前31位高频腧穴(频率>10次)可分为9个有效聚类群。【结论】针刺治疗小脑共济失调形成了以“调神束骨,熄风止动”为主要治则,以远近配穴为主体的配伍规律,并重视多气多血之阳经的应用,呈现以风池-完骨-天柱为核心的基础穴位处方。Objective To explore the acupoint selection rules of acupuncture treatment for cerebellar ataxia using data mining techniques.Methods Taking the related literature of acupuncture treatment of cerebellar ataxia as the retrieval content,the computer retrieval of China National Knowledge Internet(CNKI),China Biomedical Literature Database(SinoMed),Wanfang Data Knowledge Service Platform(Wanfang),China Science and Technology Journal Database(VIP),American Biomedical Information Retrieval System(PubMed)and other major databases.The eligible acupoints in the literature were entered into the Microsoft Excel 2021 software table to establish a database of acupoints frequency,meridian tropism,specific acupoints,distribution sites and other information for acupuncture treatment of cerebellar ataxia.SPSS Modeler 18.0 Apriori algorithm,SPSS Statistics 25.0 and SPSS Modeler 18.0 Web complex network were used to analyze the association rules of the included prescription acupoints,Ward cluster analysis and draw the tree diagram and the Web network diagram of high-frequency acupoints and core prescriptions.Results(1)A total of 93 articles were included,including 117 acupuncture prescriptions and 172 acupoints,with a total frequency of 1199 times of acupoints.(2)The top 10 acupoints were Fengchi(GB20),Zusanli(ST36),Hegu(LI4),Baihui(DU20),Sanyinjiao(SP6),Taichong(LR3),Quchi(LI11),Yanglingquan(GB34),Wangu(GB12),and Tianzhu(BL10).(3)The top five meridians used frequently were gallbladder meridian of foot shaoyang,governor vessel(GV),stomach meridian of foot yangming,large intestine meridian of hand yangming and bladder meridian of foot taiyang.(4)The selection of acupoints is mainly based on the head,face,neck and lower limbs.(5)The highest frequency of the use of specific points is the intersection point.(6)The high-frequency acupoints for acupuncture treatment of cerebellar ataxia are Fengchi-Wangu,Fengchi-Tianzhu and Fengchi-Tianzhu-Wangu.The top 31 high-frequency acupoints(frequency>10 times)can be divided into nine effective clu

关 键 词：针刺 小脑共济失调 数据挖掘 选穴规律 调神束骨 熄风止动 远近配穴 

分 类 号：R246.9[医药卫生—针灸推拿学]