丹东地区800例泌尿系结石患者结石成分分析  

Analysis of composition in 800 cases of urinary stones in Dandong region

作　　者：陈旭东[1] 李颖[2] 赵磊[1] 张洑源 谷德刚 荆闯 吴煦忱 刘万凯 于时超 CHEN Xudong;LI Ying;ZHAO Lei;ZHANG Fuyuan;GU Degang;JING Chuang;WU Xuchen;LIU Wankai;YU Shichao(Department of UrologyⅡ,Dandong Central Hospital,Dandong 118002,China;Department of Lithotripsic Section,Dandong Central Hospital,Dandong 118002,China)

机构地区：[1]丹东市中心医院泌尿外二科,辽宁丹东118002 [2]丹东市中心医院碎石科,辽宁丹东118002

出　　处：《大连医科大学学报》2024年第3期206-210,共5页Journal of Dalian Medical University

基　　金：丹东市市级基金项目(丹科发[2021]28号)。

摘　　要：目的探讨丹东市中心医院收治的泌尿系结石患者发病特点及结石成分,为本地区泌尿系结石病的防治策略提供相关的科学依据。方法收集丹东市中心医院2019年9月至2023年12月收治的800例泌尿系结石患者的临床资料,总结不同性别、年龄患者的患病情况和结石类型,并应用红外线光谱自动分析系统对结石标本进行成分分析,比较不同结石类型患者性别、结石部位的差异。结果男性泌尿系结石的患病率较高,男、女比为1.82∶1,好发于上尿路(88.75%);21~30岁患者中男性较女性多(P<0.05),31~50岁及61岁以上患者中上尿路结石发病率高于下尿路(P<0.01)。结石成分中一水草酸钙检出率最高(71.38%)。单一成分结石214例(26.75%),其中一水草酸钙74例(9.25%);无水尿酸60例(7.50%),在男性患者及上尿路中多见。混合型结石586例(73.25%),其中一水草酸钙+二水草酸钙最多,共324例(40.50%),且发生于上尿路患者多于下尿路(P<0.001);此外,一水草酸钙+碳酸磷灰石、二水草酸钙+无水尿酸的结石类型也均于上尿路多见(P<0.05)。结论丹东地区泌尿系结石病患者性别、年龄、结石部位存在差异,结石成分多以草酸钙为主,混合型结石检出多见,了解本地区泌尿系结石成分构成对泌尿系结石的防治有重要意义。Objective To investigate the characteristics of urolithiasis and the composition of stones in patients treated at Dandong Central Hospital,and to provide a scientific basis for the prevention and treatment of urolithiasis.Methods Clinical data were collected from 800 patients with urinary stones treated at Dandong Central Hospital from September 2019 to December 2023.Stone composition analysis,combined with gender,age,stone location and other related factors were performed for comparative analysis.Results The incidence rate was higher in males,with a male-to-female ration of 1.82∶1.Upper urinary tract stones were more common(88.75%).There were more male patients than female patients in the age group of 21-30(P<0.05).The incidence of upper urinary tract stones was higher in patients aged 31-50 and those over 61 than that of lower urinary tract stones(P<0.01).Among the stone components,calcium oxalate monohydrate had the highest detection rate(71.38%).There were 214 cases(26.75%)of single-component stones,including 74 cases(9.25%)of calcium oxalate monohydrate and 60 cases(7.50%)of anhydrous uric acid,which were more common in male patients and the upper urinary tract.Mixed stones were found in 586 cases(73.25%),with calcium oxalate monohydrate+calcium oxalate dihydrate being the most common combination(324 cases,40.50%),and they occurred more frequently in the upper urinary tract than in the lower urinary tract(P<0.001).In addition,stone types of calcium oxalate monohydrate+carbonate apatite and calcium oxalate dihydrate+anhydrous uric acid were also more common in the upper urinary tract(P<0.05).Conclusion There are differences in gender,age and stone location among patients with urinary calculi in Dandong region.Calcium oxalate is the predominant component,with mixed stones being more common.Understanding the composition of urinary stones in Dandong is of great significance for the prevention and treatment of urolithiasis in this region.

关 键 词：泌尿系结石 结石成分分析 丹东地区 

分 类 号：R691.4[医药卫生—泌尿科学]