儿童重症肺炎支原体肺炎诊疗建议——中山大学附属第三医院儿童重症肺炎支原体肺炎临床诊疗规范  

Recommendations for diagnosing and treating severe Mycoplasma pneumoniae pneumonia in children:clinical practice protocols from the Third Affiliated Hospital of Sun Yat-sen University

作　　者：杨可鑫 潘莉[1,2] 曾锦清 李中科 李旭锋 祝铃萍 梁英 杨丽芬[1,2] 张昆[3] 戴敏[1,4] 陈壮桂[1,2] 黎雅婷[1,2] YANG Kexin;PAN Li;ZENG Jinqing;LI Zhongke;LI Xufeng;ZHU Lingping;LIANG Ying;YANG Lifen;ZHANG Kun;DAI Min;CHEN Zhuanggui;LI Yating(Children’s Medical Center,the Third Affiliated Hospital of Sun Yat-sen University,Guangzhou 510630,China;Pediatric Intensive Care Unit,the Third Affiliated Hospital of Sun Yat-sen University,Guangzhou 510630,China;Department of Acupuncture and Moxibustion,the Third Affiliated Hospital of Sun Yat-sen University,Guangzhou 510630,China;Department of Traditional Chinese Medicine,the Third Affiliated Hospital of Sun Yat-sen University,Guangzhou 510630,China)

机构地区：[1]中山大学附属第三医院儿童医学中心,广东广州510630 [2]中山大学附属第三医院儿科重症监护室,广东广州510630 [3]中山大学附属第三医院针灸科,广东广州510630 [4]中山大学附属第三医院中医科,广东广州510630

出　　处：《新医学》2024年第7期489-496,共8页Journal of New Medicine

基　　金：国家自然科学基金(32370191);广东省自然科学基金(2019A1515011441);广东省适宜技术推广项目(202303290932258761);广东省医学科学技术研究基金(A2021386)。

摘　　要：肺炎支原体肺炎是我国5岁及以上儿童常见的社区获得性肺炎。尽管大多数患儿预后良好,但部分病例因病原体耐药或混合感染等因素发展为重症,生命受到严重威胁,并可能遗留不同程度的后遗症。中山大学附属第三医院儿童医学中心结合现行指南、共识和自身实践经验,提出了重症肺炎支原体肺炎治疗“412”集束化治疗策略,即抗感染、抗炎症风暴、抗凝和抗氧化应激治疗,中西医结合治疗,呼吸管理和随诊管理的集束化方案,为儿童重症肺炎支原体肺炎的诊疗提供参考。Mycoplasma pneumoniae pneumonia(MPP)is a common cause of community-acquired pneumonia in children aged 5 and older in China.Although most affected children have favorable clinical prognosis,some cases can escalate into severe MPP due to risk factors such as pathogen resistance or co-infections,etc.These severe cases significantly jeopardize the lives of children and may lead to diverse long-term sequelae.In response to this challenge,the Children’s Medical Center of the Third Affiliated Hospital of Sun Yat-sen University,integrating current guidelines,expert consensus,and its extensive clinical experience,has devised the“412”cluster treatment strategy.This comprehensive approach encompasses treatments for anti-infection,anti-inflammatory storm,anticoagulation and antioxidant stress.Additionally,it seamlessly integrates traditional Chinese medicine with western therapies,featuring bundled respiratory management and follow-up care.This strategy provides a valuable reference for the diagnosis and treatment of severe MPP in children.

关 键 词：重症肺炎支原体肺炎 重症肺炎 儿童 集束化治疗 

分 类 号：R725.6[医药卫生—儿科]