颈动脉周围脂肪密度与颈动脉斑块CT易损特征的相关性研究  

Correlation between pericarotid fat density and CT vulnerability characteristics of carotid plaque

作　　者：胡梦雪 余苗 孟闫凯 王强 李中林 徐凯 HU Mengxue;YU Miao;MENG Yankai;WANG Qiang;LI Zhonglin;XU Kai(Department of Radiology,the Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu Province 221006,China;School of Medical Imaging,Xuzhou Medical University,Xuzhou,Jiangsu Province 221004,China;Department of Neurosurgery,the Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu Province 221006,China)

机构地区：[1]徐州医科大学附属医院影像科,江苏徐州221006 [2]徐州医科大学医学影像学院,江苏徐州221004 [3]徐州医科大学附属医院神经外科,江苏徐州221006

出　　处：《实用放射学杂志》2024年第7期1052-1055,共4页Journal of Practical Radiology

基　　金：江苏省卫生健康委员会老年健康科研项目(LKM2022018);江苏省中医药科技发展计划项目(MS2021100);重点研发计划社会发展级“双碳”专项社会发展项目(KC23263);徐州医科大学附属医院科研项目(2022ZL25)。

摘　　要：目的探讨颈动脉周围脂肪密度(PFD)与颈动脉斑块CT易损特征之间的相关性。方法回顾性分析78例患者的临床及影像学资料。在图片存储与传输系统(PACS)上测量PFD、颈部皮下脂肪密度(SNFD)以及斑块密度、管腔狭窄程度、斑块最大厚度,计算PFD/SNFD比值。依据斑块成分分为4个亚组,即脂肪斑块组、纤维斑块组、钙化斑块组和混合斑块组。依据狭窄程度分为无/轻中度狭窄组和重度狭窄/完全闭塞组。比较临床指标、PFD、SNFD及PFD/SNFD比值在不同分组差异。结果脂肪斑块组PFD/SNFD比值[0.54(0.32,0.72)]低于钙化斑块组[0.74(0.56,0.96)],差异有统计学意义(P=0.005)。重度狭窄/完全闭塞组PFD/SNFD比值(0.51±0.29)低于无/轻中度狭窄组(0.67±0.27)(P=0.001);重度狭窄/完全闭塞组PFD[-39.75(-61.13,-24.00)]高于无/轻中度狭窄组[-61.75(-72.00,-45.38)](P<0.001)。结论PFD、PFD/SNFD比值与颈动脉斑块的易损性相关。Objective To investigate the correlation between pericarotid fat density(PFD)and carotid plaque CT vulnerability characteristics.Methods The clinical and imaging data of 78 patients were analyzed retrospectively.PFD and subcutaneous neck fat density(SNFD),as well as plaque density,degree of lumen stenosis,and maximum plaque thickness were measured on picture archiving and communication system(PACS),and PFD/SNFD ratio was calculated.The plaques were divided into 4 subgroups according to their composition,namely fatty plaque group,fibrous plaque group,calcified plaque group and mixed plaque group.The groups were divided into no/mild-to-moderate stenosis group and severe stenosis/complete occlusion group according to the degree of stenosis,and the differences between groups were compared for clinical indices,PFD,SNFD and PFD/SNFD ratio,respectively.Results The PFD/SNFD ratio[0.54(0.32,0.72)]in the fatty plaque group was lower than that in the calcified plaque group[0.74(0.56,0.96)],with a statistically significant difference(P=0.005).The PFD/SNFD ratio in the severe stenosis/complete occlusion group(0.51±0.29)was lower than that in the no/mild-to-moderate stenosis group(0.67±0.27)(P=0.001),and the PFD in the severe stenosis/complete occlusion group[-39.75(-61.13,-24.00)]was higher than that in the no/mild-to-moderate stenosis group[-61.75(-72.00,-45.38)](P<0.001).Conclusion PFD,PFD/SNFD ratio are correlated with carotid plaque vulnerability.

关 键 词：CT血管成像 颈动脉周围脂肪密度 颈部皮下脂肪密度 易损斑块 

分 类 号：R543.4[医药卫生—心血管疾病] R814.43[医药卫生—内科学] R816.1[医药卫生—临床医学]