CT细胞外体积分数在急性胰腺炎诊断及分型中的应用价值  

Application value of CT extracellular volume fraction in diagnosis and classification of acute pancreatitis

作　　者：王丽雯 欧阳富盛 黄锡谊[2] 潘佳玲 陈铭 周兰妮 胡秋根 郭保亮 WANG Liwen;OUYANG Fusheng;HUANG Xiyi;PAN Jialing;CHEN Ming;ZHOU Lanni;HU Qiugen;GUO Baoliang(Department of Radiology,Shunde Hospital of Southern Medical University,Foshan,Guangdong Province 528308,China;Department of Clinical Laboratory,Lecong Hospital of Shunde District,Foshan,Guangdong Province 528315,China)

机构地区：[1]南方医科大学顺德医院放射科,广东佛山528308 [2]佛山市顺德区乐从医院检验科,广东佛山528315

出　　处：《实用放射学杂志》2024年第7期1091-1095,共5页Journal of Practical Radiology

基　　金：广东省医学科学技术研究基金项目(A2023204);佛山市顺德区医学骨干人才培养项目(601001);佛山市自筹经费类科技创新项目(2220001004816,2220001004195);南方医科大学顺德医院临床研究启动计划项目(CRSP2022005);南方医科大学顺德医院科研启动计划项目(SRSP2021021);广东省普通高校特色创新类项目(2023KTSCX022)。

摘　　要：目的探讨基于增强CT获得的细胞外体积分数(ECV)在急性胰腺炎诊断及分型中的应用价值。方法回顾性分析行增强CT检查急性胰腺炎(急性胰腺炎组)患者及正常对照(对照组)资料。测量其增强前、平衡期胰腺及同层面腹主动脉的CT值,并计算胰腺ECV。分别进行对照组与急性胰腺炎组、非重型与重型胰腺炎2个亚组之间参数的比较。具有组间差异的参数纳入logistic回归分析,筛选急性胰腺炎、重型胰腺炎的危险因素。采用受试者工作特征(ROC)曲线分析其诊断效能。结果增强前、平衡期胰腺CT值、ECV为急性胰腺炎独立危险因素(P<0.05)。ECV为重型胰腺炎独立危险因素(P<0.05)。ECV在这2组中的诊断价值均较高,曲线下面积(AUC)分别为0.81、0.68。结论基于增强CT获得的ECV作为一个定量参数,在急性胰腺炎的诊断及分型中具有较高的临床应用价值,具有更高的普及性。Objective To investigate the application value of extracellular volume fraction(ECV)obtained from enhanced CT in diagnosis and classification of acute pancreatitis.Methods The clinical data from patients with acute pancreatitis(acute pancreatitis group)and normal controls(control group)underwent enhanced CT were analyzed retrospectively.The CT values of pancreas and abdominal aorta in the same sclice on precontrast and equilibrium-phase images were measured,and then pancreatic ECV was calculated.The measured parameters were compared between the groups of control and acute pancreatitis,and subgroups of non-severe and severe pancreatitis.The logistic regression analysis was used to identify the risk factors for acute pancreatitis and severe pancreatitis,and the receiver operating characteristic(ROC)curve was used to analyze the diagnostic efficiency in diagnosis and classification of acute pancreatitis.Results The pancreatic CT value and ECV were independent risk factors for acute pancreatitis(P<0.05),and the ECV was an independent risk factor for severe pancreatitis(P<0.05).The area under the curve(AUC)of ECV was higher in acute pancreatitis group(0.81)and severe pancreatitis subgroup(0.68).Conclusion As a quantitative parameter,the ECV obtained from enhanced CT has higher clinical application value and higher popularity in the diagnosis and classification of acute pancreatitis.

关 键 词：急性胰腺炎 重型胰腺炎 细胞外体积分数 计算机体层成像 

分 类 号：R657.51[医药卫生—外科学] R814.42[医药卫生—临床医学]