“三低对比剂”联合能谱CT技术对门静脉和肝静脉一体成像的可行性研究  

Feasibility study on integrated imaging of portal vein and hepatic vein with“three low-contrast agents”combined with energy spectrum CT technology

作　　者：吴晶晶 普伦庆 李桂华 高正阳 唐太松 毕俊宏 彭雅丽 杨禧 徐浩然 WU Jingjing;PU Lunqing;LI Guihua;GAO Zhengyang;TANG Taisong;BI Junhong;PENG Yali;YANG Xi;XU Haoran(Department of Radiology,the First People’s Hospital of Honghe State,Honghe State,Yunnan Province 661199,China;Department of Trauma Surgery,the First People’s Hospital of Honghe State,Honghe State,Yunnan Province 661199,China;Department of General Surgery,Weishan County People’s Hospital,Dali State,Yunnan Province 672400,China)

机构地区：[1]红河州第一人民医院放射科,云南红河州661199 [2]红河州第一人民医院创伤外科,云南红河州661199 [3]巍山县人民医院普外科,云南大理州672400

出　　处：《实用放射学杂志》2024年第7期1175-1178,共4页Journal of Practical Radiology

基　　金：青岛大学医疗集团科研专项项目(YLJT20212002)。

摘　　要：目的探讨“三低对比剂”联合能谱CT技术对门静脉、肝静脉一体成像的可行性。方法选取行腹部CT增强扫描的患者100例,随机分为2组:实验组(n=50)患者以3 mL/s的流速、1.2 mL/kg的总量,注入等渗对比剂碘克沙醇(320 mg I/mL),于门静脉期行能谱CT扫描;对照组(n=50)患者以5 mL/s的流速、1.5 mL/kg的总量,注入次高渗对比剂碘海醇(350 mg I/mL),行常规多期螺旋CT增强扫描。比较2组间门静脉和肝静脉的图像质量、辐射剂量。结果实验组门静脉主干CT值高于对照组,差异有统计学意义(P<0.05)。门静脉主干对比噪声比(CNR)、门静脉主干信噪比(SNR)、肝静脉CT值、肝静脉CNR 2组间差异无统计学意义(P>0.05)。对照组肝静脉SNR、图像噪声(SD)优于实验组,差异有统计学意义(P<0.05),2组门静脉、肝静脉主观评分无统计学差异(P>0.05)。实验组门静脉期能谱CT扫描容积CT剂量指数(CTDIvol)、剂量长度乘积(DLP)、有效剂量(ED)低于对照组常规单期螺旋CT扫描(P<0.05)。结论“三低对比剂”联合能谱CT技术可在门静脉晚期实现门静脉和肝静脉一体成像并减少辐射剂量。Objective To explore the feasibility of integrated imaging of portal vein and hepatic vein with“three low-contrast agents”combined with energy spectrum CT technology.Methods A total of 100 patients with enhanced abdominal CT scans were selected.The patients were randomly divided into two groups.The patients of experimental group(n=50)were injected with the isotonic contrast agent iodixanol(320 mg I/mL)at a flow rate of 3 mL/s and a total volume of 1.2 mL/kg,and underwent energy spectrum CT scan in the portal venous phase.The patients of control group(n=50)were injected with the sub-hypertonic contrast agent iohexol(350 mg I/mL)at a flow rate of 5 mL/s and a total volume of 1.5 mL/kg,and underwent conventional multi-phase spiral CT enhancement scan.The image quality and radiation dose of portal vein and hepatic vein were compared between the two groups.Results The CT value of main portal vein in the experimental group was higher than that in the control group,and the difference was statistically significant(P<0.05).There was no statistical significance in main portal vein contrast-to-noise ratio(CNR),main portal vein signalto-noise ratio(SNR),hepatic vein CT value,and hepatic vein CNR between the two groups(P>0.05).The SNR and image standard deviation(SD)of the hepatic vein in the control group were better than those in the experimental group(P<0.05).There was no statistical significance in the subjective scores of portal vein and hepatic vein between the two groups(P>0.05).The volume CT dose index(CTDIvol),dose length product(DLP),and effective dose(ED)of the portal venous phase spectrum CT scan in the experimental group were lower than those of the conventional single-phase spiral CT scan in the control group(P<0.05).Conclusion“Three low-contrast agents”combined with energy spectrum CT technology can realize integrated imaging of portal vein and hepatic vein in late portal vein,and can reduce radiation dose.

关 键 词：计算机体层成像 门静脉 肝静脉 辐射剂量 

分 类 号：R814.42[医药卫生—影像医学与核医学] R322.47[医药卫生—放射医学] R981[医药卫生—临床医学]