压缩感知3D液体衰减反转恢复增强扫描在肿瘤脑转移检出的应用价值  

Application value of compressed sensing contrast enhanced 3D fluid attenuated inversion recovery in the detection of tumor brain metastases

作　　者：卢立凤 田碧童 陈婷[1] LU Lifeng;TIAN Bitong;CHEN Ting(Department of Radiology,the Second Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China)

机构地区：[1]重庆医科大学附属第二医院放射科,重庆400010

出　　处：《实用放射学杂志》2024年第7期1184-1188,共5页Journal of Practical Radiology

摘　　要：目的探讨压缩感知(CS)3D液体衰减反转恢复(FLAIR)增强扫描在肿瘤脑转移检出的应用价值。方法选取行MRI头部增强检查60例恶性肿瘤患者,先行常规平扫和3D T1WI增强,对比剂注射后5 min进行CS 3D FLAIR扫描,由2名放射科高年资医师进行质量等级评估和病灶检出数目分析,并测量>5 mm病灶对比噪声比(CNR),采用SPSS 22.0进行Kruskal-Wallis(H)、Mann-Whitney U秩和及配对t检验分析,P<0.05为差异有统计学意义。结果3组序列采集图像质量综合评估经检验,差异无统计学意义(H=3.843,P=0.416);最终确定脑转移病例32例,共121个病灶,其中常规平扫发现89个,增强3D T1WI检出103个,CS 3D FLAIR检出112个,3组序列图像对不同大小病灶数目显示总体比较,差异有统计学意义(H=88.421,P<0.05),CS 3D FLAIR与常规平扫和增强3D T1WI差异均有统计学意义(P<0.05)。结论3D FLAIR增强扫描可更好地显示肿瘤脑转移和脑实质小微病灶,提高脑转移瘤的诊断准确率,结合CS技术可提高扫描速度,对临床诊治恶性肿瘤具有重要意义。Objective To explore the application value of compressed sensing(CS)contrast enhanced 3D fluid attenuated inversion recovery(FLAIR)in the detection of tumor brain metastases.Methods Sixty patients with malignant tumors who underwent head MRI enhancement examination were selected.Routine plain scan and contrast enhanced 3D T1WI were performed first,and CS 3D FLAIR scan was performed 5 min after contrast agent injection.The image quality were graded and the number of lesions were summarized by two senior radiologists.The contrast-to-noise ratio(CNR)of lesions greater than 5 mm was measured.SPSS 22.0 was used for Kruskal-Wallis(H),Mann-Whitney U rank sum and paired t-test analysis,and P<0.05 was significant difference.Results There were no significant differences in image quality among the 3 sequences(H=3.843,P=0.416).Among 121 brain metastases(n=32),there were 89 lesions detected by routine plain scan,103 lesions detected by contrast enhanced 3D T1WI,and 112 lesions detected by CS 3D FLAIR.Overall comparison of number of lesions with different sizes detected by three sequences was significant difference(H=88.421,P<0.05).There were statistically significant differences between CS 3D FLAIR and routine plain scan and contrast enhanced 3D T1WI,respectively(P<0.05).Conclusion Contrast enhanced 3D FLAIR can better display tumor brain metastases and small metastases in brain parenchyma and improve the diagnostic accuracy of brain metastases.Combined with CS technology,it improves scanning speed,which has important clinical value for diagnosing and treat the malignancy.

关 键 词：压缩感知 液体衰减反转恢复 肿瘤 脑转移 

分 类 号：R445.2[医药卫生—影像医学与核医学] R739.41[医药卫生—诊断学]