体外膈肌起搏器联合间歇式训练在慢性阻塞性肺疾病急性加重期患者肺康复中的应用  

Application of extracorporeal diaphragm pacemaker combined with intermittent training in pulmonary rehabilitation of patients with acute exacerbation of chronic obstructive pulmonary disease

作　　者：陶钰[1] 徐青[1] 陈玉宝[1] 俞颖[2] TAO Yu;XU Qing;CHEN Yubao;YU Ying(Department of Respiratory and Critical Care Medicine,Nanjing First Hospital,Nanjing Medical University,Jiangsu Province,Nanjing210006,China;Department of Respiratory Medicine,Nanjing First Hospital,Nanjing Medical University,Jiangsu Province,Nanjing210006,China)

机构地区：[1]南京医科大学附属南京医院南京市第一医院呼吸与危重症医学科监护室,江苏南京210006 [2]南京医科大学附属南京医院南京市第一医院呼吸内科,江苏南京210006

出　　处：《中国医药导报》2024年第16期184-187,共4页China Medical Herald

基　　金：江苏省医院协会医院管理创新研究课题(JSYGY-3-2020-299)。

摘　　要：目的探讨体外膈肌起搏器联合间歇式训练在慢性阻塞性肺疾病急性加重期(AECOPD)患者肺康复中的应用价值。方法选取2019年2月至2022年2月南京市第一医院呼吸内科门诊或急诊收治的100例AECOPD患者,采用随机数字表法将其分为对照组和试验组,各50例。对照组采用间歇式训练干预,试验组采用体外膈肌起搏器联合间歇式训练,两组均持续接受干预到出院,出院时进行效果评价。对两组膈肌功能、肺功能进行比较。结果干预后,两组膈肌活动度、膈肌增厚分数高于干预前,且试验组高于对照组,差异有统计学意义(P<0.05)。干预后,两组第1秒用力呼气量(FEV_(1))、用力肺活量(FVC)、FEV_(1)/FVC水平高于干预前,且试验组高于对照组,差异有统计学意义(P<0.05)。结论采用体外膈肌起搏器联合间歇式训练干预AECOPD患者能显著改善膈肌功能,促进肺功能康复。Objective To explore the application value of extracorporeal diaphragm pacemaker combined with intermittent training in pulmonary rehabilitation of patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods A total of 100 patients with AECOPD who were admitted to the Department of Respiratory Medicine of Outpatient or Emergency,Nanjing First Hospital from January 2019 to February 2022 were included and analyzed.They were divided into control group and experimental group by random number table method,with 50 cases in each group.The control group was treated with intermittent training intervention,and the experimental group was treated with extracorporeal diaphragm pacemaker combined with intermittent training.Patients of both groups continued to receive intervention until discharge,and the effect was evaluated at discharge.The diaphragm function and lung function were compared between two groups.Results After the intervention,the diaphragmatic activity and diaphragmatic thickening fraction of the two groups were higher than before the intervention,and the experimental group was higher than the control group,and the differences were statistically significant(P<0.05).After intervention,the forced expiratory volume in one second(FEV_(1)),forced vital capacity(FVC),FEV_(1)/FVC levels of the two groups were higher than before intervention,and the experimental group was higher than the control group,and the differences were statistically significant(P<0.05).Conclusion The use of an extracorporeal diaphragm pacemaker combined with intermittent training to intervene in AECOPD patients can significantly improve diaphragm function,promote lung function recovery.

关 键 词：慢性阻塞性肺疾病急性加重期 体外膈肌起搏器 间歇式训练 肺功能 

分 类 号：R473[医药卫生—护理学]