大川芎口服液联合西医常规治疗中风先兆患者的临床评价  

Clinical Evaluation of Dachuanxiong Oral Liquid Combined with Western Medicine in the Conventional Treatment of Patients with Stroke Threat

作　　者：邹盛鸿 曹飞鸣 ZOU Shenghong;CAO Feiming(Chongqing Kaizhou District Traditional Chinese Medicine HospitalGeriatrics,Chongqing 405400,China)

机构地区：[1]重庆市开州区中医院老年病科,重庆405400

出　　处：《中华灾害救援医学》2024年第5期557-560,共4页Chinese Journal of Disaster Medicine

摘　　要：目的探索大川芎口服液联合西医常规治疗在中风先兆患者的中的应用价值。方法回顾性分析2022年3月至2023年8月于重庆市开州区中医院就诊的70例中风患者为研究对象,根据治疗方案的不同分为观察组(大川芎口服液联合阿司匹林肠溶片和阿托伐他汀钙片)和对照组(阿司匹林肠溶片和阿托伐他汀钙片),每组35例。比较两组患者治疗前后全血黏度、纤维蛋白原水平、NIHSS和BI评分以及临床疗效。结果低切变率下,治疗后,两组患者全血黏度均显著下降(P<0.001),且观察组下降程度比对照组更显著(P<0.001)。高切变率下,治疗后,两组患者全血黏度均显著下降(P<0.001),且观察组下降程度比对照组更显著(P<0.001)。治疗后两组患者纤维蛋白原水平均显著下降(P<0.001),且观察组下降程度比对照组更显著(P<0.001)。治疗后两组患者甘油三酯(TG)水平均显著下降(P<0.001),且观察组下降程度比对照组更显著(P<0.001)。治疗后两组患者的总胆固醇(TC)水平均显著下降(P<0.001),且观察组下降程度比对照组更显著(P<0.001)。治疗后,两组患者NIHSS评分均显著下降(P<0.001),且观察组下降程度更明显(P<0.001)。结论大川芎口服液联合西医常规治疗可显著降低中风先兆患者的全血黏度和纤维蛋白原水平,改善血脂水平,有利于患者神经功能恢复,临床疗效显著。Objective To explore the application value of Dachuanxiong oral liquid combined with conventional Western medicine treatment in patients with stroke aura.Methods A retrospective analysis was conducted on 70 stroke patients who visited the Traditional Chinese Medicine Hospital in Kaizhou District,Chongqing from March 2022 to August 2023.According to different treatment plans,they were divided into theobservation group(Da Chuanxiong Oral Liquid combined with aspirin enteric coated tablets and atorvastatin calcium tablets)and the control group(aspirin enteric coated tablets and atorvastatin calcium tablets),with 35 cases in each group.Whole blood viscosity,fibrinogen level,NIHSS and BI scores,and clinical efficacy wer e compared between the two groups before and after treatment.Results With low shear rate,the whole blood viscosity of both groups decreased significantly after treatment(P<0.001),and the degree of decreasing in the observation group was more significant than that in the control group(P<0.001).At high shear rate,the whole blood viscosity of both groups decreased significantly after treatment(P<0.001),and the degree of decreasing in the observation group was more significant than that in the control group(P<0.001).After treatment,the fibrinogen level of the two groups was significantly decreased(P<0.001),and the observation group decreased more significantly than the control group decreased(P<0.001).Triglyceride(TG)levels in both groups were significantly decreased after treatment(P<0.001),and the reduction level in the observation group was more significant than that in the control group(P<0.001).Total cholesterol(TC)decreased significantly in both groups after treatment(P<0.001),and the reduction level in the observation group was more significant than that in the control group(P<0.001).After treatment,the NIHSS score of both groups decreased significantly(P<0.001),and the observation group decreased more significantly than the control group decreased(P<0.001).Conclusion Dachuanxiong oral liquid combin

关 键 词：大川芎口服液 中风先兆 全血黏度 甘油三酯类 

分 类 号：R255.2[医药卫生—中医内科学]