养阴清咽散制备工艺研究  

Preparation Process of Yangyin Qingyan Powder

作　　者：杨元凤 熊高才 杨仁惠 陈永敏 周训蓉 YANG Yuanfeng;XIONG Gaocai;YANG Renhui;CHEN Yongmin;ZHOU Xunrong(The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang 550003,China;The Third People's Hospital of Guizhou Province,Guiyang 550000,China)

机构地区：[1]贵州中医药大学第二附属医院,贵州贵阳550003 [2]贵州省第三人民医院,贵州贵阳550000

出　　处：《贵州科学》2024年第4期19-22,共4页Guizhou Science

基　　金：贵州省国内一流建设学科建设项目:(中药学)(GNYL〔2017〕008号)-子课题项目(GNYL〔2017〕008号-7-号);贵州中医药大学院内科研项目(3056-056200006)。

摘　　要：目的:确定养阴清咽散的制备工艺条件。方法:以制剂中哈巴俄苷含量、水溶性浸出物的综合评分为评价指标,优选最佳干燥工艺;以哈巴俄苷含量均匀度为指标,考察最佳混合工艺。结果:确定最佳制备工艺条件为:干燥工艺为60℃常压干燥3 h,粉碎工艺为混合粉碎,混合工艺为机器混合30 min。结论:该工艺合理,产品质量稳定,可作为养阴清咽散的制备工艺。In this study we explored the preparation process of Yangyin Qingyan Powder.The optimal drying process was determined with the harpagoside content and the comprehensive score of water-soluble extract as the indexes,and the optimal mixing process was investigated with the uniformity of harpagoside content as the index.The optimum preparation conditions were as follows:drying at 60℃under normal pressure for 3 h,mixed comminution,and machine mixing for 30 min.The process is reasonable with stable product quality,which can be used as the preparation process of Yangyin Qingyan Powder.

关 键 词：养阴清咽散 制备工艺 水溶性浸出物 哈巴俄苷 

分 类 号：R944.2[医药卫生—药剂学]