白细胞介素38在代谢综合征中的最新研究进展  

Latest research progress of interleukin-38 in metabolic syndrome

作　　者：郑轶萌 项莹[1] ZHENG Yi-meng;XIANG Ying(Department of Endocrinology and Metabolic Diseases,Second Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,150081,China)

机构地区：[1]哈尔滨医科大学附属第二医院内分泌与代谢病科,黑龙江哈尔滨150081

出　　处：《心血管康复医学杂志》2024年第4期503-507,共5页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：代谢综合征是指肥胖、高血压、高血糖、血脂异常等多种心血管疾病的危险因素在一个个体中同时存在的临床症候群。近年来慢性亚临床炎症学说备受关注,低水平的炎症状态也是导致代谢综合征的关键因素。白细胞或免疫细胞产生的细胞因子影响局部或全身炎症,这也成为了代谢综合征发病机理的重要环节。白细胞介素38作为白细胞介素1家族的最新成员,在多种炎症性疾病中显示出抗炎功能。本文旨在总结白细胞介素38在代谢综合征中的作用和最新进展研究。Metabolic syndrome refers to a clinical syndrome in which various risk factors for cardiovascular diseases such as obesity,hypertension,hyperglycemia and dyslipidemia coexist in an individual.In recent years,the theory of chronic subclinical inflammation has attracted much attention,and low-level inflammation is also a key factor leading to metabolic syndrome.Cytokines produced by white blood cells or immune cells affect local or systemic inflammation,which has also become an important link in the pathogenesis of metabolic syndrome.Interleukin 38,as the newest member of the interleukin 1 family,shows anti-inflammatory functions in many inflammatory diseases.This article aims to summarize role of interleukin 38 in metabolic syndrome and latest research progress.

关 键 词：代谢综合征X 高血糖症 肥胖症 白细胞介素38 

分 类 号：R589[医药卫生—内分泌]