机构地区:[1]北京中医药大学厦门医院,福建厦门361000
出 处:《吉林医学》2024年第8期1938-1942,共5页Jilin Medical Journal
基 金:福建省科技计划项目[项目编号:2020D018];厦门市医疗卫生指导性项目[项目编号:3502Z20209133];厦门市中医后备人才培养项目[项目编号:厦卫中医(2022)136号];。
摘 要:目的:了解厦门地区医务人员甲状腺结节(TN)的患病率和流行病特点。方法:对1082名医务人员进行甲状腺超声、肺部CT筛查以及生化、甲状腺功能指标检测,同时对女性医务人员进行乳腺及妇科彩超筛查,按检测结果分为TN组与非TN组。结果:1082名医务人员中男279例,女803例,共检出TN 498例,总检出率为46.03%,女性检出率(48.82%)高于男性(37.99%),差异有统计学意义(P<0.01)。TN患病率随年龄的增长而逐步增加,其中50岁以上组患病率最高,女性TN检出率高于男性,其中在30~39岁、40~49岁差异有统计学意义(P<0.01)。与非TN组比较,TN组合并脂肪肝、肺结节的概率高于TN组,差异有统计学意义(P<0.05);在生化指标等方面,两组在空腹血糖、血脂(总胆固醇、三酰甘油、低密度脂蛋白、高密度脂蛋白)、游离三碘甲状腺原氨酸(FT3)、血清游离甲状腺素(FT4)方面比较,差异无统计学意义(P>0.05),但非TN组肌酐高于TN组,促甲状腺激素(TSH)低于TN组,差异有统计学意义(P<0.05),TN的危险因素包括性别、年龄、TSH。对于女性医务人员,与非TN组比较,TN组合并脂肪肝、肺结节、子宫肌瘤、乳腺结节的概率高于TN组,差异有统计学意义(P<0.05),女性医务人员TN的危险因素包括年龄、子宫肌瘤、乳腺结节。结论:厦门地区医务人员是甲状腺结节高发人群,尤其是中青年女性医务人员,性别、年龄、TSH是医务人员TN高发危险因素,而女性医务人员年龄、子宫肌瘤、乳腺结节是医务人员TN高发危险因素。Objective To investigate the prevalence and epidemiological characteristics of thyroid nodule(TN)in medical staff in Xiamen area.Method Thyroid ultrasound,lung CT screening,biochemical and thyroid function index detection were performed on 1082 medical staff,and breast and gynecological color ultrasound screening were performed on female medical staff.Results Among 1082 medical personnel,279 males and 803 females,TN 498 cases were detected,the total detection rate was 46.03%,the detection rate of female(48.82%)was higher than that of male(37.99%),the difference was statistically significant(P<0.01).The prevalence of TN increased gradually with the increase of age,and the prevalence was the highest in the group over 50 years old.The detection rate of TN in females was higher than that in males,and the difference was statistically significant in 30-39 years old and 40-49 years old(P<0.01).Compared with non-TN group,the probability of fatty liver and lung nodules in TN group was higher than that in TN group,and the difference was statistically significant(P<0.05).In terms of biochemical indexes,there were no statistically significant differences in fasting blood glucose,blood lipids(total cholesterol,triglycerides,low density lipoprotein,high density lipoprotein),FT3 and FT4 between the two groups(P>0.05),but creatinine in the non-TN group was higher than that in the TN group,and TSH was lower than that in the TN group,with statistical significance(P<0.05).The risk factors of TN include gender,age and TSH.For female medical staff,compared with non-TN group,the probability of fatty liver,lung nodules,uterine fibroids and breast nodules in TN group was higher than that in TN group,and the difference was statistically significant(P<0.05).The risk factors for TN in female medical staff included age,uterine fibroids and breast nodules.Conclusion The medical staff in Xiamen area is the population with high incidence of thyroid nodule,especially the middle-aged and young female medical staff.Gender,age and TSH are the high
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