我国HIV阳性人群生殖道沙眼衣原体感染的Meta分析  

Meta analysis of genital Chlamydia trachomatis infection in HIV positive individuals in China

作　　者：樊庆莹[1] 黄李成 温桂春 陈祥生[2] 邓勇峥 FAN Qingying;HUANG Licheng;WUN Guichun;CHEN Xiangsheng;DENG Yongzheng(Business Management Department,Chronic Disease Prevention and Control Hospital,Shenzhen,Guangdong 518000,China;Hospital for Skin Diseases,Institute of Dermatology Chinese Academy of Medical Sciences,Peking Union Medical College,Nanjing,Jiangsu 210042,China)

机构地区：[1]深圳市宝安区慢性病防治院业务管理科,广东深圳518000 [2]中国医学科学院北京协和医学院皮肤病研究所,江苏南京210042

出　　处：《社区医学杂志》2024年第12期429-434,共6页Journal Of Community Medicine

摘　　要：目的系统评价我国人类免疫缺陷病毒(HIV)阳性人群生殖道沙眼衣原体感染(GCT)状况,为卫生部门开展防控工作提供基线数据及科学循证依据。方法检PubMed、Embase、中国知网、中国生物医学文献数据库、万方数据库中涉及我国HIV阳性人群GCT感染的横断面研究,检索时间为建库至2023-04-30。按照美国卫生保健质量和研究机构(AHRQ)评分标准,评价纳入研究的质量,使用R4.2.1软件进行Meta分析。结果本次研究共纳入12篇文献,纳入文献发表时间跨度为2010-2022年,研究时间跨度为2005-2021年。Meta分析结果显示,我国HIV阳性人群合并GCT感染率为7.51%(95%CI:3.54%~12.68%),感染率较高。多部位采样标本[24.56%(20.81~28.51)]高于拭子[10.84%(7.69~14.43)]和尿液[3.12%(1.20~5.81)],均P<0.001;男男性行为者(MSM)人群高于其他人群、调查年份在2015年之后高于调查年份在2015年之前、华南地区高于华中地区、华北地区、西南地区、华东地区、东北地区。结论建议未来兼顾HIV和GCT两方面,在HIV人群中常规进行GCT的筛查,根据不同地区的经济发展水平、卫生资源条件及人群特征制定相应的筛查策略,对于合并感染者加强随访和管理。Objective To systematically evaluate the infection status of genital Chlamydia trachomatis(GCT)among HIV-infected population in China,and to provide baseline data and scientific evidence-based basis for health departments to carry out prevention and control work.Methods The cross-sectional studies involving GCT infection in HIV-infected population were searched from PubMed,Embase,CKNI,SinoMed and Wanfang databases from the establishment of the database to April 30,2023.The quality of included studies was evaluated according to AHRQ scoring criteria,and Meta-analysis was performed using R4.2.1.Results A total of 12 studies were included in this study,the publication time span of the included literature was 2010-2022,and the research time span was 2005-2021,with a total of 2610 HIV-infected pepole.The results of meta-analysis showed that the GCT infection rate in HIV-infected population was 7.51%(95%CI:3.54%-12.68%),which was relatively high..The infection rate of multiple site sampling specimens[24.56%(20.81-28.51)]was higher than that of swabs[10.84%(7.69-14.43)]and urine[3.12%(1.20-5.81)],both P<0.001;The population of men who have sex with men(MSM)was higher than other populations,the survey year after 2015 was higher than the survey year before 2015,and the South China region was higher than the Central China region,North China region,Southwest region,East China region,and Northeast region.Conclusions The infection rate of GCT is high among HIV-infected population.In the future,taking into account both HIV and GCT,the corresponding screening strategies were developed according to the economic development level,health resource conditions and population characteristics in different regions.

关 键 词：艾滋病病毒 沙眼衣原体 META分析 感染状况 

分 类 号：R691.3[医药卫生—泌尿科学]