Gensini评分系统在老年冠状动脉粥样硬化病变进展中的价值  

Value of Gensini scoring system in progression of coronary atherosclerotic lesions in elderly patients

作　　者：王魁风 韩运峰 刘丽霞 Wang Kuifeng;Han Yunfeng;Liu Lixia(Department of Internal Medicine,Zhoukou Orthopaedic Hospital,Zhoukou 466000,China;不详)

机构地区：[1]周口骨科医院内科,周口466000 [2]中国人民解放军总医院第八医学中心心内科,北京100091 [3]中国人民解放军联勤保障部队第九八四医院内科,北京100094

出　　处：《中国循证心血管医学杂志》2024年第5期611-614,共4页Chinese Journal of Evidence-Based Cardiovascular Medicine

摘　　要：目的评估老年人群中Gensini评分系统对于冠状动脉粥样硬化进展中的作用。方法收集自2010年1月至2019年10月于中国人民解放军总医院第一医学中心、第七医学中心收治的老年冠状动脉粥样硬化性心脏病(冠心病)患者456例作为研究对象,根据随访冠状动脉造影与基线比较的进展程度,分为进展组(n=83)和非进展组(n=373)。观察比较两组患者基线临床资料、随访血脂变化,统计分析两组间Gensini评分的差异性价值。结果与非进展组患者相比,既往心肌梗死病史、C反应蛋白(CRP)水平升高、单核细胞计数增多均是老年患者冠状动脉病变进展的危险因素。进展组总胆固醇(TC)、非高密度脂蛋白胆固醇(nHDL-C)在基线及随访造影时均明显高于非进展组(P<0.05)。老年冠状动脉粥样硬化病变进展组与非进展组相比,进展组Gensini评分明显高于非再狭窄组(66.2±43.8)分vs.(46.7±33.1)分,风险比(HR)为1.47(1.2~-1.79)。结论本研究初步证实Gensini评分作为临床常用的冠状动脉评分系统,在老年人群中冠状动脉粥样硬化病变的进展中具有重要预测价值。Objective To review the effect of Gensini scoring system in the progression of coronary atherosclerotic lesions in elderly patients.Methods The patients with coronary heart disease(CHD,n=456)were chosen from the First Medical Center and the Seventh Medical Center of Chinese PLA General Hospital from Jan.2010 to Oct.2019.According to the progression of coronary angiography(CAG)and baseline comparison,the patients were divided into progression group(n=83)and non-progression group(n=373).The clinical baseline data and follow-up changes in blood fat were observed and compared in 2 groups.The difference in value of Gensini scores was statistically analyzed between 2 groups.Results The risk factors of progression of coronary atherosclerotic lesions included previous myocardial infarction(MI)history,increased C-reactive protein(CRP)and higher monocyte count.The levels of total cholesterol(TC)and non-high-density lipoprotein-cholesterol(nHDL-C)in baseline and follow-up CAG were significantly higher in progression group than those in non-progression group(P<0.05).The Gensini scores were significantly higher in progression group than those in non-progression group[(66.2±43.8)vs.(46.7±33.1),HR=1.47(1.2~-1.79)].Conclusion It is preliminarily confirmed thatGensini scores,as common coronary artery scoring system in clinic practice,have important predictive value to the progression of coronary atherosclerotic lesions in elderly patients.

关 键 词：动脉粥样硬化 老年 GENSINI评分 

分 类 号：R543.5[医药卫生—心血管疾病]