滋肾育胎丸联合低分子肝素及黄体酮治疗早期先兆流产患者的临床研究  

Clinical study of Zishen yutai pill combined with low molecular weight heparin and progesterone in the treatment ofearly threatened abortion

作　　者：余卢妹 Yu Lumei(Department of Gynecology,Changan Hospital,Dongguan 523800,China)

机构地区：[1]东莞市长安医院妇科,广东东莞523800

出　　处：《实用妇科内分泌电子杂志》2024年第18期48-50,99,共4页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探究滋肾育胎丸联合低分子肝素及黄体酮治疗早期先兆流产患者的临床效果。方法选取60例早期先兆流产患者,采用随机数字表法分为对照组(低分子肝素加黄体酮治疗)与研究组(滋肾育胎丸联合低分子肝素及黄体酮治疗),每组30例,比较两组临床疗效、中医证候积分、血清激素[孕酮(P)、雌二醇(E_(2))、β-人绒毛膜促性腺激素(β-HCG)]水平。结果治疗后,研究组患者的治疗总有效率为96.67%,与对照组的76.67%相比较高(P<0.05)。两组患者阴道出血、小腹坠胀、腰酸胀痛中医证候积分降低,且研究组低于对照组(P<0.05)。两组患者的血清P、E_(2)、β-HCG水平显著提升,且研究组高于对照组(P<0.05)。结论针对早期先兆流产患者,滋肾育胎丸联合低分子肝素及黄体酮治疗具有显著疗效,能改善患者中医证候积分,提高患者的血清激素水平。Objective To explore the clinical effect of Zishen yutai pill combined with low molecular weight heparin and progesterone in the treatment of early threatened abortion.Methods 60 patients with early threatened abortion were selected and divided into control group(low molecular weight heparin plus progesterone treatment)and study group(Zishen yutai pill combined with low molecular weight heparin and progesterone treatment)by random number table method,with 30 cases in each group.The clinical efficacy,TCM syndrome scores,serum hormone levels[progesterone(P),estradiol(E_(2)),β-HCG]of the two groups were compared.Results After treatment,the total effective rate of the study group was 96.67%,which was higher than that of the control group 76.67%(P<0.05).The scores of TCM symptoms such as vaginal bleeding,lower abdominal distension and lumbago distension were lower in two groups,and the study group was lower than the control group(P<0.05).The levels of serum hormones such as P,E_(2)andβ-HCG in two groups were significantly increased,and the study group was higher than the control group(P<0.05).Conclusion For the patients with early threatened abortion,Zishen yutai pill combined with low molecular weight heparin and progesterone has a significant effect,can improve the TCM syndrome score of patients and increase the serum hormone level of patients.

关 键 词：滋肾育胎丸 低分子肝素 黄体酮 早期先兆流产 临床疗效 

分 类 号：R714.21[医药卫生—妇产科学]